
Mehandru Lab @MountSinai
@mehandrulab
We study the human mucosal immune system with a focus on IBD and HIV to determine mechanisms of disease pathogenesis and predictors of therapeutic response
ID: 1407014215559389187
https://labs.icahn.mssm.edu/mehandrulab/ 21-06-2021 16:35:31
118 Tweet
535 Followers
159 Following

Check out our new work in Science Immunology! Gut-associated lymphoid tissue targeting in IBD. New insights into vedolizumab MOA Icahn School of Medicine at Mount Sinai Lipschultz Precision Immunology Institute Mount Sinai Division of Gastroenterology


How does vedolizumab work in ulcerative colitis patients? Researchers in a new Science Immunology study say the drug targets gut-associated lymphoid tissue. Learn more: scim.ag/6Im


How does vedolizumab work in ulcerative colitis patients? Researchers in a new Science Immunology study say the drug targets gut-associated lymphoid tissue. Learn more: scim.ag/6KJ


Thank you for the highlight Science Magazine! 🔦 science.org/doi/10.1126/sc… 📄science.org/doi/10.1126/sc…


🍾CONGRATULATIONS🍾 to the fantastic Dr. Shruti Naik on winning this year's @LeoFondet award in recognition of her visionary skin research program encompassing dermatology, neuroimmunology and more! Read all about it >>> leo-foundation.org/en/2024/05/17/…

🙏🏼🙏🏼🙏🏼pumped for the naik lab move to Lipschultz Precision Immunology Institute and to be part of this vibrant and exciting community of immunologists and for the breakthrough discoveries we will make together Miriam Merad, MD, PhD brianbrown #naiklabmoveuptown


Every year, Jean-Frederic Colombel hosts the GI Division #IBD Retreat to address challenging topics in #IBD. We're proud to keep the tradition going this year at IBD Retreat 2024! Register here to join: form.jotform.com/kalish39/IBDre…


Out now 🚨 in Gastroenterology is your latest update on selective IL-23p19 inhibition in IBD! Amongst other topics featuring discussion of pathogenesis, PD/PK, efficacy, safety, positioning, and more! Together with Jean-Frederic Colombel Mehandru Lab @MountSinai & Ryan Ungaro MD MS gastrojournal.org/article/S0016-…


Celebrating our PI Dr. Nina Bhardwaj! What an amazing week; elected to the National Academy of Medicine on Monday, then selected as Inventor of the Year (Mount Sinai Innovation Awards)…we are all so proud to be in your lab! Cheers 🥂!


New research from Mehandru Lab @MountSinai describes the depletion of germinal center B cells and IgA+ plasma cells in the #GI tracts of people living with #HIV. @francescacossa1 Read more in Science #Immunology: bit.ly/3Yd0Uwg


Please RT 🙏!📢My lab at Universitat de Barcelona is seeking a highly motivated postdoc to lead an exciting new public-private collaborative project (UB, CRG, CSIC, OrikineBio) aimed at testing a potentially game-changing therapy for IBD. If interested, please contact me at [email protected].


A fantastic day celebrating the 40th anniversary of the discovery of the TCR. Check out this T cell speaker photo which includes co-discoverers Tak Mak and Mark Davis. Thanks University of Toronto, Temerty Medicine, UofT Immunology, The Princess Margaret Cancer Foundation for your support.



#Eosinophils mitigate intestinal #fibrosis while promoting inflammation in a chronic DSS colitis model and co-culture model with fibroblasts by Inge Jacobs Sara D Gianluca Matteoli Severine Vermeire Tim Vanuytsel Bram Verstockt TARGID KU LEUVEN nature.com/articles/s4159…


Tejedor Vaquero, Neuman, Mehr, Cerutti, GiulianaMagri HMar Research Institute et al. show that gut IgA1 & IgA2 subclasses co-emerge early in life, largely derive from clonally related and somatically mutated plasma cells in adults, & show unique changes in #IBS. hubs.la/Q02YM2zm0


📢Thrilled to share our work on the ontogeny, reactivity, and function of #IgA subclasses in homeostasis and #IBD! Huge thanks to Andrea, all our amazing collaborators, and Journal of Experimental Medicine for their support throughout the extended revision process! It's time to celebrate🥳!

New result from #theonlylabever Temerty Medicine University of Toronto . open access link here (until Feb 2025) sciencedirect.com/science/articl… Many thanks to @Es_cheri_chia for the excellent editorial work. Hope you will find it interesting.