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I am so excited about this collaborative project with DeshmukhLab, led by postdoc Maria Clara Zanellati and funded by Chan Zuckerberg Initiative Initiative! I’ll be talking about this tomorrow Sanford Burnham Prebys

Interested in joining the UC Berkeley faculty? Tenure track Assistant Professor position in the broadly defined areas of metabolism and the nervous system. Apply now and join our vibrant campus community!! nature.com/naturecareers/…

Bioicons.com Here is an alternative to BioRender that is TRULY FREE and actively maintained. Over 1500 vectorized images sorted by license type (all creative commons or MIT). Fully editable icons and soon they will launch an Inkscape library.

Happy to share the discovery of labile Cu(II) in cells using a sensor with metal and oxidation state selectivity led by Aidan/Carson with ⁦Donita Brady of Brady Lab UPenn⁩ ⁦Tim Su⁩ ⁩⁦College of Chemistry⁩ ⁦UC Berkeley MCB⁩ ⁦PNASNews⁩ 1/n pnas.org/doi/10.1073/pn…

Wow!!! Congratulations Nurix Therapeutics for having achieved a complete (!) response in a patient with aggressive Non-Hodgkin's Lymphoma using their using a small molecule degrader. So wonderful to see these clinical data emerge with targeted protein degradation! ir.nurixtx.com/news-releases/…

Excited to share our preprint describing the identification of several new FSP1 inhibitors that sensitize cancer cells to ferroptosis!! 🎉 This study was spearheaded by grad student Joseph Hendricks and was a terrific collaboration with Julia Schaletzky. biorxiv.org/content/10.110…

Awesome preprint from James Olzmann on the discovery of FSP1 inhibitors!

Interested in performing a pooled #CRISPR screen? Check out our new STAR Protocols w/ detailed step-by-step methods, from design to screening to analysis. Terrific work from Zhipeng Li Melissa Roberts Alyssa Mathiowetz @DavidMorgens star-protocols.cell.com/protocols/2569

So excited for my postdoc Zhipeng Li, who has accepted an Assistant Professor position in the BMB Dept at the University of Florida! They are lucky to have you!! We are all going to miss you UC Berkeley MCB and we can't wait to see all that you accomplish in your lab! 🤩🎉

Congratulations to incoming professor Zhipeng Li, a brilliant scientist and amazing labmate, mentor, and friend. Can’t wait to see what’s next for you. 😀

So excited to see our paper out describing new FSP1 inhibitors that sensitize cancer cells to #ferroptosis!! This study was spearheaded by an amazing grad student Joseph Hendricks and a terrific ongoing collaboration w/ @SJD956 & Julia Schaletzky. 🥰 🎉 cell.com/cell-chemical-…

Finally, w/ Martin Kampmann and Faraz Faghri we generated CRISPRlipid as a community driven online portal to visualize and compare genetic screen data related to lipid and membrane biology. This site complements CRISPRbrain, which focuses on screens in differentiated cells. 12/12

New work from James Olzmann and former Metabolic Biology graduate student Melissa Roberts leverages genome-edited reporter cell lines and CRISPR screens to uncover mechanisms of plin2 and lipid droplet regulation. 🤩👏 cell.com/developmental-…

Check out our latest review on ERAD just out today in Nature Reviews Molecular Cell Biology! A great collaboration with Ernst Jarosch and Thomas Sommer of Max Delbrück Center. rdcu.be/dihMq

Check out this work from our lab on genome-wide single-gene CRISPR/Cas9 knockout screens to comprehensively interrogate CFTR- F508del ERAD. biorxiv.org/content/10.110…

Happy to have contributed in a small way to this collaborative paper from Ron Kopito's lab. CRISPR screens provide insight into the ubiquitin-dependent degradation of CFTR and mechanism of the CFTR correctors tezacaftor (VX-661) and elexacaftor (VX-445). biorxiv.org/content/10.110…

Going away party for Zhipeng Li. 😭 Wishing you all the best as an Assistant Professor at the University of Florida FLORIDA! Excited to hear about all the discoveries and successes from your new lab! ☺️🤩 #selenium #ferroptosis

It was sad to say goodbye and see Zhipeng Li leave the lab yesterday...You will be dearly missed! But I am looking forward to seeing all the wonderful findings coming from your future lab! All the best as an Assistant Professor at FLORIDA! 🐊🌪️⛱️

An amazing story now available as a preprint by superstar grad student Alyssa Mathiowetz uncovering the role of a novel regulator of hepatic lipid handling! A must read for anyone interested in lipid metabolism! #lipidtime