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Interesting paper that managed to map out timing and mechanism of #melanoma developing resistance to targeted #BRAF inhibitor therapy. We need to be better about identifying when a treatment is failing, so we can switch to an alternative: sciencedaily.com/releases/2025/… via

This sounds like a novel device to enhance the ability to inject compounds directly into tumors, something that sounds simple but often isn't due to tumor location, density and accessibility: prnewswire.com/news-releases/…

#nanomedicine comes to #melanoma: a newly designed nanoparticle that enhances immune response, then biodegrades. PLUS, it is a contrast agent for MRI scans, so it could also be a #theranostic agent: statnano.com/news/74602/Sma…

Not sure yet what "hydrogel microneedles" exactly are, but they sound like a way to enhance our ability to deliver anti-tumor agents directly into the tumor microenviroment: prnewswire.com/news-releases/…

Another bispecific antibody potentially useful for #melanoma and #NSCLC treatment, targeting PD1 and IL2 variant. #IBI363 has received breakthrough designation from FDA Oncology for these two cancers. The concept is to change the immunologic tumor microenvironment and make it

A review to be published soon examines the role of lipid metabolism in #melanoma resistance to immune checkpoint inhibitor therapy: frontiersin.org/journals/oncol…

Awesome as always

Looking forward to opening this #trial for #melanoma patients Atlantic Health shortly. Thanks to Jason Luke, MD, FACP for leading the charge!

Glad to honor the incomparable #DanVonHoff at AACR #AACR2025 . His list of accomplishments are incredible, benefiting #cancer patients around the world

Off my usual topic BUT can’t recommend Ocean House highly enough. Amazing place/food/staff. Our first of what I suspect will be many visits. With AWhitman

Very honored to have helped host NJ #Senator Cory Booker at #MorristownMedicalCenter Atlantic Health. Great talk about our hospital's successes and growth, plus our plans for a Mevion Medical proton therapy center and our Atlantic Health Cancer Consortium program. It's easy to see why he has been so

We were also visited today by mayor Tim Dougherty of Morristown, NJ. He continues to be a great supporter of our #cancer program and our hospital.

New Phase 1 #ClinicalTrial to treat #melanoma with KEYTRUDA (pembrolizumab) in combination with CX-801, an Interferon-alfa-2b "prodrug". Interferon has been around for a looooonnnng time, as one of the first immunotherapies, but has been hindered by its toxicity. Not clear yet if improving

Great chart; well designed. My only comment is that the future "readouts" of clinical trials are very difficult to predict, and could swing wildly in either direction based on accrual "popularity" or lack of same

Great to meet ONCO BRUNO at #ASCO25! ASCO continues as the premier meeting for incredible advances in #cancer care, and LARVOL does a great job analyzing and presenting the information!

Apparently Amazon can alter release dates… so the #Alphaborbs book is out! It looks even better in person. Here’s the author/illustrator AWhitman reading to her grandsons. So great!

Shipping now. The illustrations are amazing, the rhymes adorable. So cool!

Two days until official release date of 6-24-2025!