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Outside my usual comfort zone. This is the amazing work of Dionnet Bhatti a graduate student who examined the defensive behavior mediated lateral septum through careful SC analysis of the CRHR2 populations. Dionnet is someone you should keep your eyes on! researchsquare.com/article/rs-683…

A brief guide to statistical analysis of grouped data in preclinical research go.nature.com/4ncNcVJ

If your adjusted p-values are capped at the smallest possible number that your computer can calculate (~ log10(p) = 307), that should be a sign that it was not a stringent statistic test. Pseudobulking goes a long way to solve this.

New #publication out with #DukeMGC generated 10x Genomics #Xenium data from the Williamson lab - one of the first Xenium papers including #postmortem #PTSD samples! 🧠📷 '#SingleCell #transcriptomic and #chromatin dynamics of the human brain in PTSD': nature.com/articles/s4158…

Michael Totty Yes, failure to control for litter effects is a major problem. We wrote a similar paper on this same topic. No one listens... unfortunately. pubmed.ncbi.nlm.nih.gov/33397279/

We’re entering a new era in brain modulation where we may able to treat brain disease and improve mental health with no wires and no genetic engineering. This study shows that it’s possible to noninvasively rewire neural activity using near-infrared light and systemically

Why do we go downstairs when we hear a scary noise at night? Postdoc Kati Rothenhoefer shows how novelty seeking & explore-exploit decision making in #macaques resolves curiosity about whether choices will lead to appetitive or aversive outcomes. biorxiv.org/content/10.110…

new preprint from our lab: Modular striatal dynamics and reciprocal inhibition orchestrate skilled action sequencing. Using high-resolution kinematics tracking and neural recordings in mice performing a water-reaching task, we found spatially distributed modules of striatal

Emerging many-to-one weighted mapping in hippocampus-amygdala network underlies memory formation nature.com/articles/s4146…

🎉 Excited to share that I’ll be joining the Department of Psychology at Miami University (OH) as a Tenure-Track Assistant Professor starting Fall 2025! Deeply grateful to my mentors Jonathan Fadok , Dr. Kokare, and Dr. Subhedar for their unwavering guidance and support.

If you're planning a study, search DANDI or OpenNeuro first to see if relevant data already exists. If you're teaching, incorporate open datasets into your curriculum, writes Ben Dichter. thetransmitter.org/open-neuroscie…

Double-blind placebo controlled trial (led by UAB faculty Dr. Timothy Garvey) demonstrates >20% weight loss with co-administration of cagrilintide (which targets amylin receptors) with semaglutide (which targets GLP-1 receptors). nejm.org/doi/full/10.10…