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New in AJE: @Brennan_Kahan and colleagues argue that estimands should be routinely used to clarify the interpretation of reported treatment effects Fan Li Michael Harhay MRC Clinical Trials Unit at UCL Suzie Cro doi.org/10.1093/aje/kw…

Very excited about this! Making the world more Bayesian!

How should you incorporate baseline data to model a rare binary outcome in your cluster trial? MV model, IPW, overlap weights, & which approach to variance estimation? See OA here: doi.org/10.1002/bimj.2… Led by recent PhD grad, Dr. Zhu, w/ Fan Li @karlahemming N. Mitra

Working with Nuala Meyer is one of the best parts of my job. I'm thrilled we can finally announce that Penn Medicine will be one of the new NIH NHLBI/@NIGMS U01 ARDS, Pneumonia, and Sepsis Phenotyping Consortium Clinical Centers!!

In a beautiful bookend to his time w/ us at Center for Causal Inference, Bryan Blette is presenting our new The Lancet Respiratory Medicine article on surrogate outcomes in pulmonary hypertension at ATS PC Assembly today! Most proud that we got these figures into a Lancet journal!! Fan Li thelancet.com/journals/lanre…

Days alive without life support and similar composite outcomes are popular in critical care RCTs. Here is an updated take on these outcomes led by Anders Granholm! rdcu.be/deRK9 @AndersPerner Fernando Zampieri @benskov Theis Lange Marie Warrer Munch @MortenHylander INCEPT

New research by @Brennan_Kahan and colleagues shows that informative cluster size may be a concern in cluster randomized clinical trials. MRC Clinical Trials Unit at UCL Michael Harhay SCTorg The Patient-Centered Outcomes Research Institute Yale School of Public Health

"What Is the point of Bayesian analysis?" atsjournals.org/doi/abs/10.116… New commentary out in ATS Blue Journal with Ewan Goligher.

I am excited to share a big deliverable from our The Patient-Centered Outcomes Research Institute project, which is online early today. 'A mixed model approach to estimate the survivor average causal effect in cluster-randomized trials' OA: onlinelibrary.wiley.com/doi/10.1002/si… Fan Li Tony Guangyu TONG

Balancing Act — Probability, Precision, and the Future of Critical Care Trials in ARDS | NEJM Great editorial by ⁦⁦Ari Moskowitz MD, MPH⁩ and ⁦Michelle Ng Gong⁩! nejm.org/doi/full/10.10…

Optimal study designs for cluster randomised trials: An overview of methods and results journals.sagepub.com/doi/10.1177/09…

Pay attention to your writing quality. Clarity and simplicity impress people far more than complex and obscure prose. Remember--Simple is smart. theatlantic.com/ideas/archive/… (5/n)

A grant reviewer hurt me today.

'The Rise of Adaptive Platform Trials in Critical Care' New ATS Blue Journal led by Ewan Goligher Eddy Fan PRACTICALPlatform w/* @REMAP6 EdinUni_TRAITS INCEPT PANTHER trial @AndersPerner @msh_manu Srinivas Murthy, MD, MHSc Danny McAuley Sarina Sahetya 🔓: doi.org/10.1164/rccm.2… *tagged my best

Treatment Effect Heterogeneity in Acute Kidney Injury Incidence Following Intravenous Antihypertensive Administration for Severe Blood Pressure Elevation During Hospitalization bit.ly/3CEO9n1 #OpenAccess Lama Ghazi, MD PhD Michael Harhay Liangyuan Hu Aldo J. Peixoto, MD F. Perry Wilson, MD MSCE

Deeply honored and grateful to receive the Jo Rae Wright Award and to be part of the American Thoracic Society (ATS) and ATS Blue Journal family! #RespiratoryScience #ATS2025