The PhonoGraft acts as a medium for the patient’s own eardrum tissue to grow over and repair itself. buff.ly/3konbVy

Congratulations to Daniel Rubin, PhD/MD candidate in @yhgrad lab who finished the Boston Marathon in 2:35:46, finishing 248 among 24,819 finishers.

Honored and grateful to share The Kavli Prize with incomparable Huda Zoghbi, Harry Orr, and Jean-Louis Mandel: inspirations to this developmental neuroscientist to try human genetics. Glory and gratitude to Walshlab folks past and present HHMI Allen Frontiers Boston Children's

Tonight we welcomed the amazing 2022 entering class of The Harvard/MIT MD-PhD Program students. The future of compassionate patient care and breakthrough science is in the best of hands! Wishing you a transformational physician-scientist training experience Harvard Medical School Massachusetts Institute of Technology (MIT)! #doubledocs

The day has come! Tomorrow is the first day of medical school Harvard Medical School for our newest The Harvard/MIT MD-PhD Program trainees. Here, they “strike a pose” that would make Madonna proud. Godspeed to this next generation of physician-scientist leaders as they begin their professional journey.

Thrilled to share that my first first-author manuscript is now on bioRxiv! We deciphered a new function for an understudied Golgi-resident scaffold protein in regulating PUFA-phospholipid metabolism and ferroptosis susceptibility. 1/6 biorxiv.org/content/10.110…

Our correspondence on the 2022 outbreak of cholera in Haiti was just published in NEJM. As of Dec 7th, the outbreak had caused more than 13,000 suspected cases and 250 deaths. nejm.org/doi/full/10.10… Please read the excellent thread 🧵by @DrLouiseIvers: (1/6)

Check out this amazing (and beautifully animated) work on the mechanistic and structural details of R2 retrotransposons by the extraordinary Max Wilkinson and Chris Frangieh ! Congrats also to the R2 team of years past Michelle Walsh Alim Ladha

Love the talent and heart showcased by our Harvard Medical School and Harvard School of Dental Medicine students, and what an incredible showing by our The Harvard/MIT MD-PhD Program students! A glimpse of the school’s joie de vie for our newly admitted students! youtu.be/ioov2Ns2LAU

Excited to share our review of non-viral, protein-based nanoparticle systems for nucleic acid delivery, recently published in Biomaterials with Elliot Chaikof! A short 🧵 (1/7): authors.elsevier.com/c/1iN3MWWN0wV8s

SO thankful for the experiences I’ve had over the past 2 years with my amazing classmates @HarvardMed @MIT_HST 🥹💛🥹💛 Next stop: my first clinical rotation (internal medicine) !!👩‍⚕️💪

Check out this amazing detective story led by Max Wilkinson that I got to help with! After some crazy initial ideas like ssDNA translation :P, Max found a reconsituted promoter (was lucky to watch in person visting Boston last year) and the rest of the mechanism quickly followed

Groundbreaking work by an outstanding Harvard Medical School HST MD-PhD student Sayo Eweje BIDMC Department of Surgery BIDMC

Had lots of fun sprinting on Evo as my first big project at Stanford, with an awesome team of Eric Nguyen, Michael Poli, Matt Durrant, Brian Kang, Dhruva Katrekar, Patrick Hsu, and Brian Hie! I generated and experimentally tested new ssDNA transposons using Evo (14/48 worked :O)

1/ Thrilled to share an advancement in gene therapy from my PhD in Nature Communications! We've developed a new approach to reduce immune responses while maintaining efficiency—paving the way for safer, more effective therapies. Big thanks to Feng Zhang & Mirco J. Friedrich! bit.ly/redicas9

Thrilled to see this work out in the world and excited to see where it takes us next!

Can we use RNA to insert kilobases of DNA into the human genome, opening up a new way to engineer cells or treat disease? Excited to share our latest work turning a retrotransposon (a “jumping gene” with an RNA intermediate) from songbirds into a genome editing tool. 🧵 (1/7)