🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

This becoming a tradition! We are inviting students and postdocs broadly interested in computational cancer to 2025 NCI Spring School on Algorithmic Cancer Biology. Happening Mar 10-14. Please apply and spread the word: ncifrederick.cancer.gov/events/confere…

Most excited to see our study presenting the mechanism driving ~50% of osteosarcomas (LTA #chromothripsis) out in Cell! How does the final version differ from the preprint? x.com/isidrolauscher… Buckle up!! -tons of new exciting results ahead! 👇👇

Now online! Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution dlvr.it/THMMjr

New online! Diversity and consequences of structural variation in the human genome bit.ly/4g1ZQSQ

Happy to share our paper in Nature Communications with Oscar Florez-Vargas Ozkar and team! We explore a VNTR as a functional GWAS lead for bladder and many other cancers, and show mechanism in cancer, telomere length, and longevity nature.com/articles/s4146…

Severus detects somatic structural variation and complex rearrangements in cancer genomes using long-read sequencing go.nature.com/3R334eH

Excited & very lucky to be part of the Gates Sr. AD Fellowship ✨ Using CARD’s long-read epigenetic data 🧬 to build better predictive models of ADRD & making all models & methods openly available (open science FTW!🔓). Looking forward to collaborating with this awesome group!

SPECIAL ISSUE Part 2! This month Genome Research publishes a diverse collection of articles offering novel biological and clinical insights gained using long-read DNA and RNA sequencing technologies and other long molecule approaches. tinyurl.com/Genome-Res-35-4

New preprint on hifiasm (ONT)! We can now achieve near T2T human genome assembly using only ONT Simplex reads—in just half a day, with or without ultra-long sequencing. biorxiv.org/content/10.110…

High-quality metagenome assembly from nanopore reads with nanoMDBG biorxiv.org/content/10.110… #biorxiv_bioinfo

Assemblies of long-read metagenomes suffer from diverse errors biorxiv.org/content/10.110… 🧬🖥️🧪

Call for Papers! Genome Research is now encouraging submissions for a Special Issue on The Genetics and Genomics of Somatic Mosaicism, Guest Edited by Drs. Gilad Evrony, Eunjung Alice Lee, and Raheleh Rahbari. tinyurl.com/Call-for-paper… #BOG25 #KSMosaicism25 #MITS25 #somaticmosaicism

🔬 Meet SLIDE-EX: an #AI model that predicts cell type-specific gene expression and abundance directly from histopathology slides. 🧬 No #RNA #sequencing needed. Just images. 🧵1/8 biorxiv.org/content/10.110…

Three-dimensional genome landscape of primary human cancers nature.com/articles/s4158… #journals #feedly

Bioinformatics folks: check out our bioRxiv on a new, very efficient and accurate system for automated genome annotation, EviAnn, led by Aleksey Zimin biorxiv.org/content/10.110…

Announcing myloasm, a new long-read (ONT R10/PacBio) metagenome assembler. With Heng Li. myloasm-docs.github.io

SSACB 2025 rescheduled to Aug 18-22! We are inviting students and postdocs broadly interested in computational cancer to 2025 NCI Summer School on Algorithmic Cancer Biology. Please apply and spread the word: ncifrederick.cancer.gov/events/confere…

Our RiNALMo RNA language model has been published in Nat Comm nature.com/articles/s4146… Great work by Rafael Josip Penić and Tin Vlašić, with support and patience in teaching us RNA biology from Roland G Huber and Yue Wan RiNALMo is already an SOTA as a benchmark for RNA LLMs.