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Proud and excited of the work that Alexander Himstead is doing with our team by characterizing and deciphering the heterogeneity of aggressive non-functional Pituitary Neuroendocrine tumors and laying down the foundation for exciting future scientific work at UC Irvine Neurosurgery 🧪 🧫 🧬 🔬

2024 has been an incredibly big year! Looking forward to all the challenges that 2025 has to bring and thankful to serve the brain tumor patients of Southern California with the incredible clinicians, scientists, staff and especially residents at UCI Health who are committed

2024 has been an incredibly big year! Looking forward to all the challenges that 2025 has to bring and thankful to serve the brain tumor patients of Southern California with the incredible clinicians, scientists, staff and especially residents at UCI Health who are committed

Non-functioning Pit-NETs are among the most common pituitary tumors we operate on due to mass effect. Our group is committed to characterizing their heterogeneity and patterns of invasion and growth using WHO transcription factor profiling to determine the underlying mechanisms

No limits 🚀

Happy Valentines Day from #NASBS2025 🫶🏽UC Irvine Neurosurgery NASBS

Grateful to share the stage with these awardees and honored to receive the Career Development Award from the NASBS. Their continued recognition of our groups clinical and basic science research pushes us to remain curious about the diseases that affect our patients.

Beautiful said 🫶🏽

What a treat to have Wenya Linda Bi visit us at UCI … such an incredible leader in our field, with humility and a commitment to patient outcomes that should inspire all of us 🙏🏽

If you are a foreign medical school graduate yearning for an opportunity, or an American medical school graduate privileged to be living it; if you are a physician in search of the best for your patients or simply a human who is trying to understand our interconnectedness, search

In a recent study (May 2025) published in Nature Genetics, Nomura et al.(Roel Verhaak , Lavarone, Mario Suva , Tirosh Lab labs) leveraged single-nucleus RNA sequencing and bulk tumor DNA sequencing to unveil new dimensions of GBM complexity. The team discovered three previously

“Facts are the air of scientists.” In an excellent editorial, Dr. E. Antonio Chiocca, MD, PhD, FAANS argues for preservation of research time in neurosurgery training, because today's protected time creates tomorrow's breakthroughs. CNS Neurosurgery Publications AANS Link:journals.lww.com/neurosurgery/f…

Must Watch! 💎💎💎

It’s my favorite time of the year when we celebrate the outgoing and incoming future of neurosurgery. Congratulations to our graduating Chiefs, Jordan and Alvin, and our graduating fellows Tigran and Nolan. You know you are doing something right as a program when every year you

Higher volume helps. 📊 Our new analysis of ~15,000 patients undergoing endoscopic transsphenoidal surgery (ETSS) for pituitary tumors published in Journal of Neurosurgery shows: 🏥 Higher institutional volume --> lower risk •Major complications steadily drop as case volume rises until ~58

Beautiful work by DrJFM - Juan C. Fernandez-Miranda MD - group showing the variations of the CCL and patterns of pituitary tumor invasion! This knowledge is key to deliver outcomes like this in a recent patient who presented with 3rd and 6th nerve palsies. Resecting the medial wall and decompressing

🚨 New in Neuro-Oncology Advances: Epigenetics—not mutations—may drive pituitary tumor growth. Our review highlights how DNA methylation patterns influence PitNET behavior, classification, and treatment potential. #NeuroOncology #PitNET #Epigenetics #Neurosurgery #Pituitary