🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

➡️Thrilled to share 🤩 our work now 🔥HOT OF THE PRESS in Cell (read n’ share, it’s open access!): "Repeat-based holocentromeres influence genome architecture and karyotype evolution" #epigenetics #centromere #chromatin #polyploidy 🔗 bit.ly/3zVw2p1 🧵[1/]

Our new data show that plant centromeres can be engineered. We seeded CENH3 to synthetic repeat arrays, causing chromosome breakage. Fragments passed through meiosis formed neochromosomes with synthetic centromeres and were faithfully transmitted. bit.ly/3RWm7pV

Viruses...assemble! Check out our new 3D printed model to demonstrate virus symmetry and self assembly. #lovevirology #3Dprinting

Epigenetics, chromosome biology, and haploid induction: excited to celebrate the memory of Simon Chan with a great set of talks at the Simon Chan Celebration Symposium, Jan 19 2023, UC Davis. In person or by zoom webinar.

TRASH: Tandem Repeat Annotation and Structural Hierarchy doi.org/10.1093/bioinf… New methods paper from us reporting an algorithm to de novo map tandem repeats and their higher order structures - we benchmark against Arabidopsis and human T2T genomes github.com/vlothec/TRASH

Understanding centromere diversity in Arabidopsis - Privileged to contribute to such a remarkable collaborative effort, and excited to explore these emerging unknowns! Thread below on what we found.

We have a 4-year Biotechnology and Biological Sciences Research funded NRPDTP PhD position on RNA modifications and gene expression. If you are excited about genetics, embryonic development and Oxford Nanopore sequencing, do apply. Funding is for UK students only. #RNA #phd @biouea Earlham Institute biodtp.norwichresearchpark.ac.uk/projects/regul…

Structural variation and DNA methylation shape the centromere-proximal meiotic crossover landscape in Arabidopsis biorxiv.org/content/10.110… new preprint from us on genetic & epigenetic features that control crossovers close to the Arabidopsis centromeres

📢New job alert !!📢 We've an exciting opportunity for a Postdoc Research Associate to develop translational synthetic strategies to control recombination - in the Genetic and Epigenetic Inheritance in Plants Group with Ian Henderson ! Read more and apply👇 jobs.cam.ac.uk/job/42002/

I have an advert for a postdoc @MRC_LMB out. The project will be to develop a universal biomolecular force field for molecular simulation. Feel free to email me to discuss informally. findapostdoc.com/search/job-det…

🌱Are you interested in climate change and how plants can adapt to stress?☀️ Fully funded @socobiodtp #PhD in my lab School of Biosciences, University of Kent University of Kent in beautiful Canterbury (UK) Feel free to contact me to know more! southcoastbiosciencesdtp.ac.uk/project/hybrid… Deadline: 8th January 2024 RT🙏 1/n #scijob

Interested in plant xip? I have a #PhDposition to join my group Life Sciences in early 2024. Aim of the project- dissect a new molecular pathway that controls axillary #meristem formation. Funded by University of Warwick and Limagrain. Open to UK/International students.

Structural variation and DNA methylation shape the centromere-proximal meiotic crossover landscape in Arabidopsis doi.org/10.1186/s13059… New paper from us Genome Biology

Happy to share our review on The structure, function, and evolution of plant centromeres genome.cshlp.org/content/early/… Genome Research

I'm absolutely thrilled to share that our work on human centromere variation and evolution has been published in nature! We completely sequenced all centromeres from a second human genome & compared them to those from the first complete human genome, uncovering new sequences,

Exciting news! I'm honoured to have been awarded the 2024 New Phytologist Tansley Medal! Grateful to the community, mentors, and collaborators who have supported me throughout my career #TansleyMedal #PlantScience

Bridging the gap: Unravelling #plant centromeres in the telomere-to-telomere era #TansleyInsight by Matt Naish, winner of the 2024 New Phytologist #TansleyMedal for excellence in #PlantScience. 👇 📖 nph.onlinelibrary.wiley.com/doi/10.1111/np… #LatestIssue Wiley Plant Science

Centrophilic retrotransposon integration via CENH3 chromatin in Arabidopsis nature from Tetsuji Kakutani & colleagues - beautiful insights into control of transposon insertion into the centromeres nature.com/articles/s4158…

🌱 Egg cell-specific degradation of CENH3 using engineered E3-ligases successfully induce haploids ⚠️ Preprint from Andreas Houben's lab Leibniz IPK 👉🏼 Gametophytic degradation of CENH3 - a synthetic biology approach for haploid induction in plants 📖doi.org/10.21203/rs.3.…

🚨New paper, now published in nature! Using pan-genetics across the Solanum genus🍅🥔🍆we reveal why gene duplications🧬are major contingencies in crop engineering. My postdoc work in the Lippman lab Cold Spring Harbor Laboratory, in collab. with Michael Schatz and many others! nature.com/articles/s4158…