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Glycosylation is complicated, diverse and important

Wow

Cell free ftw

It's weird not to be part of iGem this year, after a 6 years of Macquarie_Australia... but from my brief browse of the finalist wikis, I hope Flavoflow, Vilnus-Lithuania wins! Lateral flow devices, edible vaccines, and fish health, who would have thought! #iGEM2020 #GiantJamboree

So happy to share! We designed from scratch barrels with 8 beta-strands that fold in lipid membranes. To succeed, we had to extensively use negative design and destabilize the beta-strands to maintain the proteins unfolded in water. science.sciencemag.org/content/371/65…

A fancy piece of work! Was not aware that glycans can affect bacterial quorum sensing. Thread's a pretty quick summary

Less is more

This twirling work of science is special ✨ AFAIK, it's the first crystal structure of a functional #protein fully designed by #AI A milestone in our quest to use language models to generate proteins that are unseen in nature & can function well in the real-world. Read below👇

Today with EMBL-EBI, we're launching the #AlphaFold Protein Structure Database, which offers the most complete and accurate picture of the human proteome, doubling humanity’s accumulated knowledge of high-accuracy human protein structures - for free: dpmd.ai/alphafolddb 1/

Took a while, but it is finally out. Thanks Professor Sugar Prof Mark Hutchinson for the chance to work on these rare long term intrathecal CSF samples #glycotime academic.oup.com/glycob/advance…

Bunch of scientists looking for bioluminescence ARC Centre of Excellence in Synthetic Biology #CoESB23

After 24 hours of traveling (not including transit time 🙄), finally arrived in Brno for the 2024 MSB conference. Pretty strong #glycotime turn out in the talks for a non-glyco focused conference that glycofolks can consider next time. msb2024.org/program-schedu…

After a good conference in Brno, moving on to the 4th Canadian glycomics symposium in Edmonton #CGS2024. Venue, weather and talks so far are great!

Been a long time since I really enjoyed a poster session in a conference. Good quality stuff GlycoNet #CGS2024

Experimentally Determined Diagnostic Ions for Identification of Peptide Glycotopes #JProteomeRes pubs.acs.org/doi/10.1021/ac…

Excited to share our latest research published in Nature, revealing the crucial role of the brain's extracellular matrix in obesity and diabetes. nature.com/articles/s4158… Thanks to Cait Beddows, Edward Moh, University of Melbourne & our funding partners NHMRC, Australian Research Council and Diabetes Australia