Join our team as a postdoctoral fellow. If you are interested in DNA replication and genome stability, please check out the details below: #DNA replication #Replication fidelity

Profound synthetic lethality between SMARCAL1 and FANCM dlvr.it/TGcsSD

ANNOUNCEMENT! PhD and Int MSc-PhD programme admissions TIFR Hyderabad: Physics, Chemistry, and Biology-oriented programmes Further details available here: gsadmissions.tifrh.res.in/applicants/

Applications invited for the position of a pre-primary teacher at the Child Care Centre TIFR Hyderabad. Interested candidates are requested to write to [email protected].

#ResearchHighlight Ritesh Haldar's (Ritesh Haldar) research group TIFR Hyderabad has developed a porous thin-film catalyst incorporated into a cross-flow microfluidic system for enhanced catalytic activity. This study has been published in Nature Communications.

Unlocking protein networks with Predictomes: The SPOC advantage dlvr.it/TJkDqX

Over the years we engineered many cell lines expressing various Cas9/dCas9 fusions constitutively or inducibly. I am not ATCC, but if they can be useful to your research, you can get in touch (email, no DM). For some lines you may need an MTA from third parties.

ZBP1 senses spliceosome stress through Z-RNA:DNA hybrid recognition dlvr.it/TKWXWk

We are #hiring! Position: Junior Research Fellow, in a project under the National Quantum Mission, led by G. Rajalakshmi 🔬 Project Focus: Quantum Sensing & Metrology | Alkali-Atom-Based Atomic Magnetometer | Lab-to-Field Prototyping | Industry Collaboration Apply by May 26th!

Emerging mechanisms underlying formaldehyde toxicity and response dlvr.it/TLFjKQ

Online Now: The immortality mechanism of TERT promoter mutant cancers is self-reinforcing and reversible dlvr.it/TLKCPC

Absolutely crazy month for progress in the world of genome instability & DNA repair, especially as pertaining to aging. A few of the most exciting papers, a 🧵:

Really excited to share our new study, where we identified ZNF280A, a novel regulator of homologous recombination during DNA repair, linked to the human 22q11.2 distal deletion syndrome. A special shout out to Thomas Clarke for leading the project! nature.com/articles/s4155…

We are delighted to welcome Aniruddha Panda (Aniruddha Panda), who joins TIFR Hyderabad as the newest faculty member. With native mass spectrometry, lipidomics, proteomics & metabolomics, he is exploring how cellular biochemistry governs signalling & how its disruption leads to disease.

So you want to change transgene expression: just change your promoter, right? Changing the promoter increases RNA and thus protein levels. What more could be happening? [1/n] Well, promoters don’t just set RNA levels; they uniquely transform how RNAs are transmitted into protein

Online Now: Regulation of somatic hypermutation by higher-order chromatin structure dlvr.it/TLbXqm

New online! Structural variants in the 3D genome as drivers of disease bit.ly/44FiIo5

A study in nature reports on the development of a method to trace intercellular transfer of mitochondria and demonstrates that cancer cells that receive mitochondria from neurons have enhanced metastatic capabilities. go.nature.com/4keoh1k

We are #hiring! Applications are invited for the position of a Junior Research Fellow in the field of high sensitivity electron spin resonance spectroscopy using superconducting circuits. This position is available in Vishal Ranjan's lab. Last date to apply: July 31, 2025

A new review just out with John Diffley and Janet Iwasa provides high resolution videos of the earliest stages of DNA replication in eukaryotes, the formation of pre-Replicative Complexes. Comparison of mechanisms in yeast and human cells is presented. See rdcu.be/et5Uh