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New online! Disentangling clinical and biological trajectories of neurodegenerative diseases go.nature.com/4dhLLjv

BMA Students Joe Wilson 🩺 BMA Medical Academics I can see why this seems like progress but still pretty devastating for clinical academia, which thrives on getting experience in new places and bringing your experience to a new place. Indeed that's what the research world encourages. That's what it brought for me!

As ascertained by the literature, OGM has consistently demonstrated higher sensitivity towards tumours with HRD, and its applicability also includes the overall chromosomal characterization of gliomas. Glad that our narrative review was able to highlight this point!

Doctors in Northern Ireland are falling behind those in the rest of the UK - DDRB uplifts need to be paid to all doctors in NI at the same time and at the same level as the other nations!

A recent study unpicks a key immune-mediated mechanism of mutant IDH–blocking drugs such as vorasidenib in the treatment of IDH-mutant glioma. Learn more in a new Clinical Implications of Basic Research article: nej.md/4f3dIMf

🧵Just in time for #FluorescenceFriday: New research from the Venkataramani lab Cell maps how brain tumor cells create extensive neural networks in glioblastoma. Check out our paper here: authors.elsevier.com/sd/article/S00… Ekin Reyhan Svenja Tetzlaff 1/15

Consultant Neurosurgeon at King's College NHS, Professor Keyoumars Ashkan, receives an MBE for services to neurosurgery.   In 2020, he removed patient Dagmar's brain tumour while she played her violin throughout the surgery. 👇

So happy to share the latest study from National Oncology Trainees Research Collaborative led by Dr Karen Mactier from NHS Lothian University of Glasgow, looking at UK-wide practice in managing a rare cancer, uterine sarcoma. 👇👇👇 pubmed.ncbi.nlm.nih.gov/39725428/

In a Comment, the International Committee of Medical Journal Editors (ICMJE) shines a light on the deceptive practices of predatory journals and the actions stakeholders can take to protect against them. hubs.li/Q031nFdv0

Academics are paid nothing for peer review. Yet journals made a total of over $8.3 billion on article processing charges alone between 2019-2023. Make it make sense.

How our gut microbiome regulates sugar preference nature.com/articles/s4156…

In the ESOPEC trial, researchers evaluated whether perioperative chemotherapy improves overall survival as compared with preoperative chemoradiotherapy in patients with resectable esophageal adenocarcinoma. Full trial results and Plain Language Summary: nej.md/4apWlo5

An impressive sleep study goes deep on links to lifestyle and diseases —impact of gut microbiome and diet re: sleep apnea —big contribution of lifestyle factors —ability to predict across 16 body systems from sleep data Nature Medicine Eran Segal Weizmann Institute

A recent study showed that morning coffee drinkers had a 12% lower risk of all-cause mortality and a 31% lower risk of dying from cardiovascular disease over a 10-year period. This benefit was specific to morning coffee drinkers, as no similar protective effects were observed

We have started construction on iREACH Health, a new world-class #ClinicalResearch centre on the Lisburn Road. It is set to open in 2027 and will create up to 1,000 jobs and generate an additional £733 million GDP for #NorthernIreland. The new centre, which is one of three

The aspartame sweetener was found to promote atherosclerosis in animal models cell.com/cell-metabolis…

#OnlineFirst: High-grade glioma: combined use of 5-aminolevulinic acid and intraoperative ultrasound for resection and a predictor algorithm for detection. thejns.org/view/journals/….

Middle East and North African countries are underrepresented in oncology clinical trials, with higher participation in observational, late-phase, and industry-funded trials, and greater representation in countries with higher GDP. ja.ma/4iA6QYm

I don’t know what to say anymore. As doctors, we can’t stop a genocide and we can’t end a famine. We provided a diagnosis - genocide. We provided a prescription to end the genocide - for Canada to end its complicity and direct involvement in Israel’s crimes now.

The world will never be the same again. None of us will recover from the horror we have watched Israel enact for over 635 days. We will never forget a minute of it. That is a promise.