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Why becoming an 'expert' is ridiculously easy I recently listened to a book publishing titan speak. Here's where he thought most people go wrong— Often, people want to write a book on a topic they are experts in. This creates a high expectation, and sufficiently high activation

what if learning about a topic was as braindead as scrolling tiktok? showed up to a hackathon 2 hours before submissions were due with no idea and no code furiously coded an app that spits out an engagement-maxxed tiktok feed for topics you want to learn about won + stole all

Just published Nature Medicine Randomized trial of tirzepatide (Mounjaro) vs placebo *after* 12 weeks of intensive lifestyle intervention and >5% weight loss nature.com/articles/s4159… At 72 weeks, Placebo group gained 2.5% weight back; GLP-1 drug lost additional 18.4% body weight

Wow Just read perhaps the greatest article about a doctors’ diagnostic skills Not in the medical literature, but in an economics journal! If you think about diagnosis, follow along It won’t disappoint Saurabh Jha

The $350M startup building perfect memory Rewind watches everything you do (in silico) and soon—will listen to everything you say—creating a perfect, GPT-queryable memory. There are two approaches to human augmentation: 👓 Restore function to normal levels e.g. glasses

Drug discovery is becoming more expensive and producing less results than ever before (Eroom's Law)—why? One of the ballooning costs are clinical trials. Pharma/biotech often outsource their trials to CROs (contract research organisations). But many CROs are incentivised to

a new AlphaFold model: in AI for biology, you get what you train for since the release of AlphaFold in 2020, a once-hypothesized revolution in drug discovery has failed to materialize. while accurate at predicting protein structure, the utility of AF for drug discovery has been

Looking to hire hungriest MD you know. Ideal candidate is highly clinically competent with top tier education, actively looking to join a startup in the earliest stages. Needs to be a doer / builder. Early in career is fine. Well funded deeply ambitious company and team.

Fascinating that in 1958, the standard of care for cardiac arrest was performing a thoracotomy + cardiac massage within 1 min 😮 youtu.be/d45HkjY1pTI?si…

🎙️ My 2023 podcast highlights! 🚀 If you're into Science, Technology, AI, and Politics, these are a must-listen: 45 Graus Ciência Sem Fim Sacani (Space Today) - AKA Gordão Foguetes NEJM AI Andrew Beam Arjun (Raj) Manrai Mustafa Sultan, MD Andrew D. Huberman, Ph.D. #Wrapped2023

So a lot of people asked what my fridge is like

This is jon ronson's 'The Psychopath Test' pitch to Ira Glass — a book which spent 10 wks on the New York Times Bestseller List ...and also convinced me to join med school wanting to become a psychiatrist. That didn't happen. But it was a pleasure learning how Jon writes.

I very much enjoyed talking with Musty!

I notice smart people always ask for feedback. They'll regularly ask: "Any feedback for me?" and they mean it. They're not fishing for compliments, they won't be happy until you give them something they can improve on. I'm working on managing my ego so I can start doing this.

A new era for Co:Helm as we introduce our new name and brand identity — Anterior. We are the AI company built by clinicians for clinicians to transform healthcare administration.

We are excited to announce that we've raised $20 million in Series A funding led by New Enterprise Associates (NEA), with participation from Sequoia Capital, Blue Lion Global and Neo.