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(ORIGINAL) Myostatin in idiopathic inflammatory myopathies: Serum assessment and disease activity. doi.org/10.1111/nan.12… Myostatin levels lower in IIM; inactive ASyS and DM have higher myostatin; in IMNM, low myostatin levels persist, indicating a new pathological mechanism.

(ORIGINAL ARTICLE) Target formation in muscle fibres indicates reinnervation – A proteomic study in muscle samples from peripheral neuropathies doi.org/10.1111/nan.12…

(SHORT COMMUNICATION) Structural synaptic signatures of #Alzheimer's disease and dementia with Lewy bodies in the male brain doi.org/10.1111/nan.12… Confocal microscopy reveals alterations in synaptic organization in the brain sample associated with neurodegeneration in dementia

(ORIGINAL) Axonal response of #mitochondria to #demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis doi.org/10.1111/nan.12… axon response of mitochondria to demyelination, highlighting potential for neuroprotective therapy

(ORIGINAL) Discrepant modulating effects of dietary #docosahexaenoic acid on cerebral lipids, fatty acid transporter expression and soluble beta-amyloid levels in ApoE−/− and C57BL/6J mice doi.org/10.1111/nan.12…

(ORIGINAL) Robust #methylation-based classification of brain tumours using nanopore sequencing doi.org/10.1111/nan.12… Nanopore sequencing enables rapid, cost-effective DNA methylation-based brain tumor classification with high accuracy and specificity.

(Short communication, Open Access) Motor neuron involvement threatens survival in spinocerebellar ataxia type 1 doi.org/10.1111/nan.12… Severe laryngeal dysfunction is the key life-threatening condition in #SCA1 due to significant motor neuron loss.

(Short communication) Fibrocartilaginous cerebral and spinal emboli: A report of two cases with histopathological confirmation doi.org/10.1111/nan.12…

(Short communication, Open Access) Soluble amyloid-β dimers are resistant to amyloid-β prion conversion in vivo suggesting antiprion properties doi.org/10.1111/nan.12… Aβ dimers inhibit Aβ prion spreading in vivo, potentially counteracting Aβ aggregation.

ORIGINAL Schwann cells and myelin in human peripheral nerve: Major protein components vary with age, axon size and pathology. doi.org/10.1111/nan.12… Protein components in Schwann cells and myelin vary with age, axon size, and nerve pathology, influencing peripheral nerve health.

(Original) Patient-derived xenograft mouse models to investigate tropism to the central nervous system and retina of primary and secondary central nervous system lymphoma doi.org/10.1111/nan.12… An in vivo model provide a basis for studying therapeutic targets for #CNS #lymphoma.

Original, Open access, Occurrence of focal myositis during #Behçet's disease: The identification of a specific vasculitis-associated focal myopathy doi.org/10.1111/nan.12… Focal myositis in Behçet's disease indicates systemic vasculitis, needing special care.

Original, Open access, TDP-43 pathology and functional deficits in wild-type and ALS/FTD mutant cyclin F mouse models doi.org/10.1111/nan.12… Mouse models expressing human #CCNF variants mirrored behavioral abnormalities and neuropathological hallmarks of #ALS and #FTD.

Original, Open access Tuberous sclerosis complex-1 (TSC1) contributes to selective neuronal vulnerability in Alzheimer's disease doi.org/10.1111/nan.12… #TSC1 dysregulation may drive selective neuronal vulnerability in #Alzheimer's disease, highlighting potential therapeutics.

(Original) Increased number and domain of interlaminar astrocytes in layer I of the temporal cortex in epilepsy doi.org/10.1111/nan.12… Astrocytic structural remodeling in layer I of the temporal cortex may play a significant role in #epilepsy.

(Original) Simultaneous Nbs1 and p53 inactivation in neural progenitors triggers High-Grade Gliomas (HGG) doi.org/10.1111/nan.12… Simultaneous inactivation of #Nbs1 and #p53 in mice promotes high-grade #gliomas, mimicking Radiation-Induced Gliomas.

(Review) Timing is everything: A connection between medulloblastoma prognosis and foetal cerebellar development doi.org/10.1111/nan.12… Survival in non-WNT/non-SHH #medulloblastoma is continuously linked to tumour transcriptional profile and foetal cerebellar development stage.

(Review) Intelligence quotient–genotype association in dystrophinopathies: A systematic review and meta-analysis doi.org/10.1111/nan.12… Becker and Duchenne muscular dystrophies associate with lower IQs, which inversely correlate with the number of affected dystrophin isoforms.

(ORIGINAL) Is Islet Amyloid Polypeptide indeed expressed in the human brain?doi.org/10.1111/nan.12… No specific expression of islet amyloid polypeptide (IAPP) in human brain tissue was found, suggesting no direct link between IAPP and Alzheimer's Disease Neuropathological Change.

(ORIGINAL) microRNA-based predictor for diagnosis of frontotemporal dementia doi.org/10.1111/nan.12… Using cell-free plasma #miRNA profiling, a model was developed to accurately distinguish frontotemporal #dementia from non-neurodegenerative controls in about 90% of cases.