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Novel Neurocognitive Testing Tool for Early Neurotoxicity Detection Following Anti-CD19 and Anti-BCMA Chimeric Antigen Receptor (CAR) T-cell Therapy: A Pilot Study - Clinical Lymphoma, Myeloma and Leukemia clinical-lymphoma-myeloma-leukemia.com/article/S2152-…

Neurological Complications of Immune Checkpoint Inhibitors: a Practical Guide, out now in Practical Neurology. Authored by several members of the NEON group.

No link between baselines congnitive performance and #ICANS onset; NfL levels independendly associated with #ICANS #carTcells #lymphoma Hôpital Saint-Louis AP-HP #PreceptorshipLymphomas

In an analysis of long term safety events in 783 patients treated with #Tcell therapy in 38 trials, 2.3% of patients developed second primary malignancies, and vector integration analyses revealed no pathological insertions nature.com/articles/s4159…

Congratulations Dr. Al Bakir Maise Al Bakir!

Researchers have demonstrated that CAR-T cells can transfer tumor-specific receptors to T cells in mice via trogocytosis, endowing recipient cells with antitumor immunity. Learn more in Science Immunology: scim.ag/40WLdfl

Hemophagocytic lymphohistiocytosis (HLH) is a severe and life-threatening syndrome characterized by overwhelming inflammation that often leads to multiorgan failure and death if not treated promptly and appropriately. Biologically, HLH has taught us about the immune system and

Two patients with refractory myeloma who had excellent antitumor responses to cilta-cel CAR T-cell therapy later had T-cell lymphomas that contained the lentivirus construct used to generate the CAR T-cell product. Brief Report on the CARTITUDE-4 trial: nej.md/4gA6G27

Diagnosis and management of immune checkpoint inhibitor neurotoxicity requires close collaboration between oncologists, neurologists and other health care professionals. @freddievonberg Anna Olsson-Brown Heather Shaw NEONeurotox

Expert Review on Neurotoxic Complications of CAR-T now out in Journal of Neurology, Neurosurgery and Psychiatry, from Freddie Vonberg, Claire Roddie Maeve O'Reilly harpreet Imran Malik and Aisling Carr. #CART #ICANS #Neurotox Free to access link: jnnp.bmj.com/cgi/rapidpdf/j…

Non-ICANS neurological complications after CAR T-cell therapies: recommendations from the EBMT Practice Harmonisation and Guidelines Committee - The Lancet Oncology thelancet.com/journals/lanon…

Addition of Phosphorous and IL6 to m-EASIX Score Improves Detection of ICANS and CRS, as Well as CRS Progression mdpi.com/3214676 #mdpicancers via Cancers MDPI

Neurotoxicity in Patients With CNS Lymphomas Treated With CAR T-Cell Therapy: A Study From the French Oculo-Cerebral Lymphoma Network hubs.la/Q03h2M1-0

Our latest editor’s choice podcast out now- exploring the neurological@complications of immune checkpoint inhibitors with an expert panel of ⭐️⭐️⭐️s!

Practical Neurology links: ▶️ Apple: podcasts.apple.com/us/podcast/how… ▶️ Spotify: open.spotify.com/episode/1wXdQ7… ▶️ Web: pnbmj.podbean.com/e/neurological…

Acute Hemorrhagic Leucoencephalitis: A Rare CNS Complication of Abrus precatorius Poisoning hubs.la/Q03jNSdp0 #NeuroX

Immune Checkpoint Inhibitor Neurotoxicity #Neurotox #NEON

⁦Freddie Vonberg⁩ does an excellent job of highlighting risk factors for prolonged ICANS in CART patients at the 2025 BNOS conference ⁦BNOS⁩ ⁦UCL Cancer Institute⁩ ⁦UCLH⁩ ⁦

Now out in print - FREE to access jnnp.bmj.com/content/96/7/6… Editor's Choice in Journal of Neurology, Neurosurgery and Psychiatry