Whole-genome sequencing of rare disease patients in a national healthcare system biorxiv.org/content/early/… #genomics

Civil society has a big part to play in changing attitudes on obesity. Big up to Jamie Oliver & Hugh Fearnley-Whittingstall - the big voices driving the public discourse on this agenda. My speech at Obesity APPG today: gov.uk/government/spe…

Extremely excited to be at London Calling 2019 #NanoporeConf

Delighted to meet and interact with bright, energetic, young scientists, innovators and entrepreneurs at the GapSummit for the Next Generation in Boston. Expect great things to happen from them.

"The Development and validation of a universal blood donor genotyping platform." doi.org/10.1182/blooda… Blood Transfusion Genomics Consortium Brigham and Women’s Research Brigham Digital Innovation Hub Harvard Medical School NY Blood Center New York Blood Center Enterprises (NYBCe) Cambridge University Sanquin Thermo Fisher - nick gleadall William Lane, MD, PhD

We created an affordable DNA-based assay for unified genotyping of red blood cell (RBC), platelet (HPA), and white cell antigens (HLA). Testing of over 7,000 blood donors showed concordances of 99.91%, 99.97%, and 99.03% for RBC, HPA, and HLA.

Example of immediate clinical benefit. Patient requiring regular blood transfusions who developed anti-E, -Coa, and -Wra blood group antigen antibodies. No known compatible blood donors. Our results found 5 compatible donors who are now providing life-saving transfusions.

Development and validation of a universal blood donor genotyping platform nhsbt.nhs.uk/research-and-d…

Congrats to Emanuele William Astle Sara Trompeter Simon Stanworth nick gleadall Mihaela van der Schaar-one of the winners in Round 2 of the Accelerated Access Collaborative @NHSX National Institute for Health and Care Research #AIAward, receiving funding through #NHSAILab. Find out more here:tinyurl.com/4dewnbhp #ArtificialIntelligence

😎

Linking in more Blood Counts! team members nick gleadall Nick Gleadall 👏

I love Dropbox because It allows for easy working in my Scientific Research environment db.tt/u0haAIb9

NEW use case for whole #genome sequencing in tomasz baniak Hemotology: more precise blood antigen typing, from William Lane, MD, PhD & our NHGRI funded #MedSeq Project, CSER NY Blood Center bit.ly/2KB8aKY "with the potential to transform the practice of transfusion medicine"