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Our researchers are working with Uni of Birmingham to develop a new method to diagnose children’s brain tumours. The 10 minute scan could be game changing for children like Jack, aged six, who was diagnosed with medulloblastoma last year. Read more 👇 ncl.ac.uk/press/articles…

'We are delighted with the outcome of this trial. Simply put, it will save lives,' Professor Colin Rees. We've been part of an exciting new trial that has found that AI shows greater efficiency in detecting early signs of bowel cancer! 🔬 #WeAreNCL ncl.ac.uk/press/articles…

Blood cancer patient finds funds for new research bbc.in/474OgDy

#Medulloblastoma survivors often live with late effects from their brain tumour & its treatment. Debbie Hicks & colleagues in @NUcancer, University of Leeds & CRUK Radnet Leeds Centre developed a model to study the late effects of treatment👉 bit.ly/4cQshRS 🧵 [1/9] #CCAM

Debbie Hicks University of Leeds CRUK Radnet Leeds Centre Medulloblastoma is the most common malignant paediatric #BrainTtumour. Advances in treatment now mean >70% of children survive for at least five years, but these treatments often cause late effects including impaired physical functioning & neurocognitive deficits. [2/9]

Debbie Hicks University of Leeds CRUK Radnet Leeds Centre More research is needed to understand the mechanisms of these late effects and begin developing new strategies to reduce them. Until now, research has been held back by a lack of available model systems for paediatric medulloblastoma radiotherapy protocols. [3/9]

Debbie Hicks University of Leeds CRUK Radnet Leeds Centre Debbie Hicks and her team have developed the first model to combine childhood medulloblastoma-style #Radiotherapy (location, dose, age) with comprehensive long-term late-effect follow-up. [4/9]

Debbie Hicks University of Leeds CRUK Radnet Leeds Centre In the model, high dose radiation is specifically targeted to the brains of young mice, closely mirroring the radiotherapy protocols used to treat childhood #Medulloblastoma. [5/9]

Debbie Hicks University of Leeds CRUK Radnet Leeds Centre Receipt of medulloblastoma-style radiation was well tolerated. : aAll mice survived with minimal acute side effects and bodyweights were no different from mice who hadn’t been given radiotherapy. [6/9]

Debbie Hicks University of Leeds CRUK Radnet Leeds Centre #Medulloblastoma survivors often have worse memory and cognitive skills. Our mice also showed worse memory function in adulthood, compared to control mice. [7/9]

Debbie Hicks University of Leeds CRUK Radnet Leeds Centre Often #Medulloblastoma survivors experience reduced motor skills and poor physical functioning. After radiation, mice were more frail, had reduced grip strength and worse balance, co-ordination and endurance. [8/9]

Debbie Hicks University of Leeds CRUK Radnet Leeds Centre We can now use our model to understand the biology underpinning #Medulloblastoma late-effects and develop new treatments and interventions, leading to better quality of life for people affected by #Cancer. You can read the full paper here 👉 bit.ly/4dMEMPY [9/9]

We are thrilled to share that Children’s Cancer North has been named ‘North East Charity of the Year’ at the #NECharityAwards!

We’re absolutely over the moon with our award win last night at the #NECharityAwards, where we were named ‘North East Charity of the Year’! Read more here: childrenscancernorth.org.uk/news/childrens…

Vital research led by our own Professor Steve Clifford could lead to treatments that improve survival rates of children diagnosed with Medulloblastoma, which is responsible for around 5% to 10% of childhood cancer deaths. 🔬 Read more here. ⬇ #WeAreNCL ncl.ac.uk/press/articles…

Looking for a PhD? Our multi-disciplinary team Newcastle University Centre for Cancer are using next-generation 'omics, AI, bioinformatics and biostatistics across pan-European clinical trials to improve outcomes for children with #medulloblastoma. See findaphd.com/phds/project/m… or DM if you're interested.

Applications for the 2025 Black Leaders in Cancer PhD Scholarship Programme is now open. This exciting programme will help to make an immediate and tangible impact on the diversity of the research workforce. ncl.ac.uk/cancer/trainin…

We are very proud that our very own Professor Christine Harrison has been deservedly recognised with an OBE for her work on improving the scientific knowledge and care of childhood leukaemia. bloodcancer.org.uk/news/blood-can…

A great opportunity for PhD study on an important cancer with supervision by one of our rising stars! findaphd.com/phds/project/p… findaphd.com/phds/project/p… findaphd.com/phds/project/p…

It was a pleasure hosting Walko Lab from the Bart's Centre for Squamous Cancer in our NUCoRE Cancer seminar series this week where he told us about his exciting research on transcriptional addiction.