If you are interested in joining the vibrant cryo-EM community in Bordeaux (@fronzes_lab, Yaser Hashem, Nicolas Reyes, Petya Krasteva, Innis Lab...), please apply to the 2022 IECB call for new group leaders. Deadline June 15! (2/2) nature.com/naturecareers/…

Congratulations to Marina Rodnina on becoming an International Member of National Academy of Sciences.🥂 The U.S. academy honors her for her innovative #research on the structure and function of #ribosomes – the protein factories of living #cells. mpinat.mpg.de/4132811/pr_221…

Collaboration of Tatyana Pestova & @joachimfrank labs Columbia University SUNY Downstate reveals the molecular architecture of 40S translation initiation complexes on hepatitis C virus #HCV #IRES by #cryoEM embopress.org/doi/10.15252/e…

Fantastic PI & great scientific environment. Postdocs join! Congrats, Jailson.

It's been a pleasure to present our new data on the structural dynamics of human translation initiation on the fantastic Ribosomes 2022 conference. Big thanks to Yaser Hashem, Innis Lab & Ignatova Lab for organizing this amazing meeting.

Today, our work in partnership with Sam Sternberg lab is published: nature.com/articles/s4158… Amazing (and hard) journey with Florian Hoffmann, PhD Jing Wang Leslie, MinJoo and more! Thanks to all for your hard work and 👇 a taste of what we saw.

It has been really a pleasure to participate in the summer school of the @Tampe_Lab and give a talk on the human #ribosome & atomic-resolution #cryoEM. Big thanks to Robert Tampé, the whole Tampé lab, Anne Halenius & Berislav Bosnjak for great scientific tales and discussions!

#cryoDRGN joins #teamtomo - cryoDRGN-ET by Ellen Zhong and co-workers: biorxiv.org/content/10.110…

I am thrilled to share our manuscript published in Nature Reviews Molecular Cell Biology. In this Review (Brito Querido et al., 2023), we discuss the current state of knowledge on eukaryotic translation initiation and its regulation in health and disease.

Great work and movie on the structure and function of eIF4A and eIF4F in the human 48S translation initiation complex, congrats!

Our new paper is finally out! We discovered that the human tumor suppressor protein Pdcd4 binds to the #mRNA entry channel in the 40S ribosomal subunit, where it blocks the eIF4F-independent role of eIF4A. #ribosome #CryoEM UMich RNA Center 〽️🧬 UMLifeSciences nature.com/articles/s4146…

Last week my main project was published at Nature Communications, so there is a thread about our findings: nature.com/articles/s4146…

Ever wondered what else to do with your 3D printer? Here we used it to simulate #ribosome subunit joining in presence of the large eIF3 complex. Read our full #cryoEM story on the human 48S translation initiation machinery @Naturesmb: doi.org/10.1038/s41594…

Happy to share our little discovery with Simone Mattei team on how ribosomes hibernate upside down on mitochondria during cellular stress is now out Nature Communications! A collaboration between @medicineUVA, @EMBL, EMBL Imaging Centre, MEMC. Congrats to all authors! nature.com/articles/s4146…

Our latest work is out in nature today! Using smFRET, we directly visualized recruitment of the eIF4F complex to the 5' cap of eukaryotic mRNAs and formation of an activated mRNA. Our findings reveal new and surprising roles for each eIF4F component. 1/3 nature.com/articles/s4158…