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A study in Nature Metabolism describes how reduced dietary availability and systemic loss of cysteine leads to adipose tissue browning and rapid weight loss in mice and humans. go.nature.com/442dd2p

🚨Job Alert!🚨 Nature Metabolism seeks an Associate or Senior #Editor to join our team. If being a #Metabolism Editor is for you, and you are based in, or open to moving to New York or Shanghai, check out our #job posting below and apply before June 11th! springernature.wd3.myworkdayjobs.com/SpringerNature…

GLP-1-mediated synaptic plasticity in feeding regulation is modulated by energy state go.nature.com/3TgUkTf

NEWS&VIEWS | Peter Arner (Karolinska Institutet) Under acute #stress, adipose tissue #lipolysis causes release of #GDF15 from local macrophages, which, in turn, binds to the receptor GFRAL in the #brain, evoking #anxiety 🐭 nature.com/articles/s4225…

A food-sensitive olfactory circuit drives anticipatory satiety go.nature.com/3FxpZgg

RESEARCH | HA Clarke, Tara, Ramon Sun et. al. (University of Florida Research) The authors study the contribution of #glycogen accumulation in the onset and progression of #lungcancer nature.com/articles/s4225…

RESEARCH | M Krapić, I Kavazović, Felix Wensveen et. al. (U Rijeka, HR) The authors dissect the mechanism by which #NKcells drive #adipose remodelling, fuelling #antiviral immune responses nature.com/articles/s4225…

REVIEW | M van Hul, P Cani et al. (UC Louvain): This Review discusses the impact of the gut #microbiota on #cancer and on cancer #therapy 🦠💊 FREE to read: nature.com/articles/s4225…

NEWS&VIEWS | SQ Crome, Sue Tsai (University of Toronto, University of Alberta) A new role for the visceral #adipose tissue and resident natural killer cells in tuning #antiviral immunity nature.com/articles/s4225…

REVIEW | Anne Loft, MP Emont, E Rosen et al. (Department of Biochemistry and Molecular Biology, The University of Chicago, Harvard Medical School): A roadmap towards achieving consensus on #singlecell transcriptomics data in #adipose tissue. FREE TO READ: nature.com/articles/s4225…

RESEARCH | Dylan Duerre, Andrea Galmozzi et al. (UW–Madison): Inhibition of haem synthesis is shown to lead to the accumulation of branched-chain amino acids in the brown adipose tissue of mice, which impairs #thermogenesis 🐭🌡️ nature.com/articles/s4225…

RESEARCH BRIEFING | Dylan Duerre, Andrea Galmozzi et al. (UW–Madison): A BCAA–haem axis regulates brown fat function 🐭🌡️ nature.com/articles/s4225…

A nitroalkene derivative of salicylate, SANA, induces creatine-dependent thermogenesis and promotes weight loss go.nature.com/3SZcRDD

RESEARCH | Z Ying, X Liu et al. (Guangzhou Medical University): The mitochondrial unfolded protein response is shown to inhibit #pluripotency during somatic cell #reprogramming. 🧫✨ nature.com/articles/s4225…

NEWS&VIEWS | M Bartez, D Chen (UC Berkeley): The mitochondrial unfolded protein response controls the mesenchymal-to-epithelial transition during the acquisition of #pluripotency. 🧫✨ nature.com/articles/s4225…

Upper-gastrointestinal tract metabolite profile regulates glycaemic and satiety responses to meals with contrasting structure: a pilot study go.nature.com/4kTPmrZ

A brief guide to statistical analysis of grouped data in preclinical research go.nature.com/4ncNcVJ

Author Correction: The sphingosine-1-phosphate receptor 1 mediates the atheroprotective effect of eicosapentaenoic acid go.nature.com/44a0rxT

RESEARCH | A Tsyben, R Mair, KM Brindle (Cambridge University): The spatial distribution of labelled metabolites in #glioblastoma samples from patients infused with 13C-glucose 🧠 nature.com/articles/s4225…

RESEARCH | YS Kao, T Sparwasser et al. (Princeton U, U Mainz): Insight into the metabolic requirements of IL-17A-producing gamma delta T cells, offering an actionable target to treat #psoriasis by inhibiting fatty acid synthesis 🧫✨ nature.com/articles/s4225…