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Very excited to read this new preprint by Lewis Evans and @LiveseyLab. They did a whole genome CRISPR screen and showed that LRRK2 regulates Tau uptake in human cortical neurons. biorxiv.org/content/10.110…

Thanks so much to all the key collaborators Vik Khurana Lab Gist Croft @peng_illinois Joseph Powell to make this effort happen. We also excited to be part of the greater Aligning Science Across Parkinson’s community to tackle mechanisms and potential treatments of #Parkinsons together

I’ve been working on Crispr screens in human neurons for the last wee bit and so my husband made me this super cool Cas9 artwork. Best gift ever!

A big moment in the quest to find a treatment for Parkinson's disease. Dopamine neurons generated from pluripotent stem cells have been approved for clinical testing. Congrats to my mentor Lorenz and the team that made this possible. More info: prnewswire.com/news-releases/…

The Lorenz lab is looking to hire two motivated Research Technicians to work on aging and Parkinson's disease as part of our Aligning Science Across Parkinson’s grant. externaltalent-mskcc.icims.com/jobs/46734/res…

Congrats to Sudha for Nature Neuroscience paper on microglia differentiation and tri-culture technology to dissect cell type-specific inflammatory cross talk in hPSC model of AD go.nature.com/3aHZAZG with Jason Tchieu, Nathalie Saurat, @harschnitz, Ryan, Gabriele & Lisa, Dana Pe'er and others

Congrats @harschnitz!!! Can’t wait to see all the cool science that comes out of your lab. Will miss you here in the Studer Lab though!

Congratulations to my amazing mentor Lorenz on his ISSCR achievement award. Very cool to be at ISSCR in person and to see him receive it. So well deserved!

Very excited to have this story out in the world! New strategies to measure and manipulate age in iPSC-derived human neurons and primary fibroblasts. Big thank you to all the authors especially co-lead and computational whiz Chao Zhang, Daniela Cornacchia, Doron Betel and Lorenz!

The GENtoniK paper is finally out in Nat Biotech! go.nature.com/3ROgdZf A chemical cocktail to drive maturation of neurons and other hPSC-derived cell types. Congrats to Emiliano, Andrew, @OberstPolina, Yana Zorina - a.k.a. NeuroBead, Arianna Baggiolini, Shuibing Chen Gabriele Ciceri and many others.

📢 Join us for the PD-AGE: ECRs Career Event - Navigating through academia! 🚀 Unlock academic success with expert advice, career insights, and Q&A sessions with Janelle Drouin-Ouellet, @benjamindehay and Emily Rocha🌟 RSVP now on docs.google.com/forms/d/e/1FAI…! #ECR #Academia #PDAGE

Why do most dopamine neurons die shortly after transplantation and how can we fix it? Excited to see our story out at Cell. Congrats to Taewan Kim & SoYeon Koo Memorial Sloan Kettering Cancer Center and to all the other collaborators who made this work possible. cell.com/cell/fulltext/…

How to trigger age-related features in hPSC neurons? In a CRISPR screen Nathalie Saurat identified neddylation inhibition as a tool to trigger hallmarks of aging in neurons and selective degeneration in AD or PD but not isogenic control neurons. @cellstemcell bit.ly/3XBxCsA

Look, it’s the Lorenz lab past and present at #ISSCR2024. Getting together is another awesome part of attending this conference 🤩

Great postdoc opportunity if you are interested in developing next gen human PSC based cell therapies for brain repair here at MSK