
INEM NECKER
@neckerinem
INEM is a biomedical research center in molecular medicine with focus on immunology, cell biology, metabolism, microbiology, and hematology.
ID: 1188359119100694528
https://www.institut-necker-enfants-malades.fr/index.php?lang=en 27-10-2019 07:39:24
582 Tweet
782 Followers
220 Following

[PUBLICATION] Treating patients with somatic PIK3R1 mutations using alpelisib leads to clinical and radiological improvement. A promising step toward targeted therapy in PIK3R1-related disorders. 📄Read more: embopress.org/doi/full/10.10… Guillaume Canaud (MD, PhD) Gabriel Morin EMBO Mol. Medicine
![INEM NECKER (@neckerinem) on Twitter photo [PUBLICATION] Treating patients with somatic PIK3R1 mutations using alpelisib leads to clinical and radiological improvement.
A promising step toward targeted therapy in PIK3R1-related disorders.
📄Read more: embopress.org/doi/full/10.10…
<a href="/CanaudLab/">Guillaume Canaud (MD, PhD)</a> <a href="/morin_gbrl/">Gabriel Morin</a> <a href="/EmboMolMed/">EMBO Mol. Medicine</a> [PUBLICATION] Treating patients with somatic PIK3R1 mutations using alpelisib leads to clinical and radiological improvement.
A promising step toward targeted therapy in PIK3R1-related disorders.
📄Read more: embopress.org/doi/full/10.10…
<a href="/CanaudLab/">Guillaume Canaud (MD, PhD)</a> <a href="/morin_gbrl/">Gabriel Morin</a> <a href="/EmboMolMed/">EMBO Mol. Medicine</a>](https://pbs.twimg.com/media/GrZAsnqXcAAigzy.jpg)

🚨 We're hiring! The IMMEDIAB Lab team is looking for: 🧪 1 Postdoc 🧬 1 Research Assistant / Bioinfo/ Tech 📍 Paris | Start Sept 2025 📄 Full details + apply: institut-necker-enfants-malades.fr/careers Dr. Fawaz Alzaid


🗓️ Join us on Friday, June 6, for a #seminar with Elvira Mass, Head of the Department of Developmental Biology of the Immune System at LIMES Institute Bonn. Prof. Mass will explore the developmental programming of tissue-resident macrophages. Don’t miss it! Nicolas Venteclef IMMEDIAB Lab


🗓️ Join us on June 13, for a #seminar with Han Li, Principal Investigator and leader of the cellular plasticity in age-related pathologies group at Institut Pasteur. Prof. Li will explore senescence induced-cellular plasticity in health & disease. Don’t miss it! Pende Mario


🚨 We're hiring at INEM! The Immunity in Health and Disease team, led by Simon Fillatreau, is recruiting: 🔬 Assistant Engineer 🧑💼 Horizon Europe Project Manager (ARTiDe project) More info & how to apply: 🔗 institut-necker-enfants-malades.fr/offre-demploi/… 🔗 institut-necker-enfants-malades.fr/offre-demploi/… Inserm



[PUBLICATION] mTORC1 governs multiciliated cell differentiation by favoring progression through a cell cycle variant without DNA replication and by acting on cytolinker proteins for centriole disjunction. 📖Read more: embopress.org/doi/full/10.10… Pende Mario
![INEM NECKER (@neckerinem) on Twitter photo [PUBLICATION] mTORC1 governs multiciliated cell differentiation by favoring progression through a cell cycle variant without DNA replication and by acting on cytolinker proteins for centriole disjunction.
📖Read more: embopress.org/doi/full/10.10…
<a href="/MarioPende/">Pende Mario</a> [PUBLICATION] mTORC1 governs multiciliated cell differentiation by favoring progression through a cell cycle variant without DNA replication and by acting on cytolinker proteins for centriole disjunction.
📖Read more: embopress.org/doi/full/10.10…
<a href="/MarioPende/">Pende Mario</a>](https://pbs.twimg.com/media/GuWvROXWsAA3sip.jpg)

🗓️ Join us on July 4, for a #seminar with David Sabatini, group leader at IOCB Prague. Dr. Sabatini will explore nutrient sensing by the mTOR pathway. Don’t miss it! Pende Mario



[PUBLICATION] New study with the Bharat lab MRC-LMB Cell Biology reveals the structure of the Neisseria meningitidis filamentous phage MDAΦ. Cryo-EM/ET show how phage bundling supports biofilm formation & pathogenesis. Mathieu Coureuil PNASNews pnas.org/doi/10.1073/pn…
![INEM NECKER (@neckerinem) on Twitter photo [PUBLICATION] New study with the Bharat lab <a href="/CellBiol_MRCLMB/">MRC-LMB Cell Biology</a> reveals the structure of the Neisseria meningitidis filamentous phage MDAΦ.
Cryo-EM/ET show how phage bundling supports biofilm formation & pathogenesis.
<a href="/MathieuCoureuil/">Mathieu Coureuil</a> <a href="/PNASNews/">PNASNews</a>
pnas.org/doi/10.1073/pn… [PUBLICATION] New study with the Bharat lab <a href="/CellBiol_MRCLMB/">MRC-LMB Cell Biology</a> reveals the structure of the Neisseria meningitidis filamentous phage MDAΦ.
Cryo-EM/ET show how phage bundling supports biofilm formation & pathogenesis.
<a href="/MathieuCoureuil/">Mathieu Coureuil</a> <a href="/PNASNews/">PNASNews</a>
pnas.org/doi/10.1073/pn…](https://pbs.twimg.com/media/Gu2sgk0XUAAcaU0.jpg)



#France2030 | Félicitations à Guillaume Canaud Guillaume Canaud (MD, PhD), lauréat d’une Chaire d’excellence en Biologie/Santé pour son projet sur les malformations vasculaires liées à KRAS. 🎯Objectif : développer des thérapies ciblées pour une médecine ultra personnalisée. 👏🏼

🎉 Congratulations to Juliane Da Graça, recipient of the 2025 Beth Levine #ThesisPrize! Her outstanding research Morel Lab🇪🇺 on the role of ER/Endosome contact sites in the regulation of #autophagy captures the award's spirit of excellence and innovation. 👏


👏🏼 Proud to see Juliane Da Graça, former PhD student at INEM, honored with the 2025 Beth Levine Thesis Prize for her outstanding work on autophagy, supervised by Etienne Morel Morel Lab🇪🇺.

[PUBLICATION] NEW in Cell Reports Juliane Da Graça et al. show that ER-endosome contacts act as hubs for phagophore formation during starvation. 📖 cell.com/cell-reports/f… Morel Lab🇪🇺
![INEM NECKER (@neckerinem) on Twitter photo [PUBLICATION] NEW in <a href="/CellReports/">Cell Reports</a>
<a href="/JulianeDaGraca/">Juliane Da Graça</a> et al. show that ER-endosome contacts act as hubs for phagophore formation during starvation.
📖 cell.com/cell-reports/f…
<a href="/MEMBRAMICS_lab/">Morel Lab🇪🇺</a> [PUBLICATION] NEW in <a href="/CellReports/">Cell Reports</a>
<a href="/JulianeDaGraca/">Juliane Da Graça</a> et al. show that ER-endosome contacts act as hubs for phagophore formation during starvation.
📖 cell.com/cell-reports/f…
<a href="/MEMBRAMICS_lab/">Morel Lab🇪🇺</a>](https://pbs.twimg.com/media/Gv-nsebX0AAhLFt.jpg)

[PUBLICATION] The Morel Lab🇪🇺 shows how Influenza A virus rewires ER lipid metabolism to promote viral ribonucleoproteins egress. 🦠 📖 journals.plos.org/plosbiology/ar… Carla Alemany Juliane Da Graça sharing the first authorship 👏🏼 w/ Institut Pasteur, since 1887 & IPNP PLOS Biology
![INEM NECKER (@neckerinem) on Twitter photo [PUBLICATION] The <a href="/MEMBRAMICS_lab/">Morel Lab🇪🇺</a> shows how Influenza A virus rewires ER lipid metabolism to promote viral ribonucleoproteins egress. 🦠
📖 journals.plos.org/plosbiology/ar…
Carla Alemany <a href="/JulianeDaGraca/">Juliane Da Graça</a> sharing the first authorship 👏🏼
w/ <a href="/institutpasteur/">Institut Pasteur, since 1887</a> & IPNP
<a href="/PLOSBiology/">PLOS Biology</a> [PUBLICATION] The <a href="/MEMBRAMICS_lab/">Morel Lab🇪🇺</a> shows how Influenza A virus rewires ER lipid metabolism to promote viral ribonucleoproteins egress. 🦠
📖 journals.plos.org/plosbiology/ar…
Carla Alemany <a href="/JulianeDaGraca/">Juliane Da Graça</a> sharing the first authorship 👏🏼
w/ <a href="/institutpasteur/">Institut Pasteur, since 1887</a> & IPNP
<a href="/PLOSBiology/">PLOS Biology</a>](https://pbs.twimg.com/media/GwDykonXUAAhC9-.jpg)