INEM NECKER (@neckerinem) 's Twitter Profile
INEM NECKER

@neckerinem

INEM is a biomedical research center in molecular medicine with focus on immunology, cell biology, metabolism, microbiology, and hematology.

ID: 1188359119100694528

linkhttps://www.institut-necker-enfants-malades.fr/index.php?lang=en calendar_today27-10-2019 07:39:24

582 Tweet

782 Followers

220 Following

INEM NECKER (@neckerinem) 's Twitter Profile Photo

[PUBLICATION] Treating patients with somatic PIK3R1 mutations using alpelisib leads to clinical and radiological improvement. A promising step toward targeted therapy in PIK3R1-related disorders. 📄Read more: embopress.org/doi/full/10.10… Guillaume Canaud (MD, PhD) Gabriel Morin EMBO Mol. Medicine

[PUBLICATION] Treating patients with somatic PIK3R1 mutations using alpelisib leads to clinical and radiological improvement.
A promising step toward targeted therapy in PIK3R1-related disorders.
📄Read more: embopress.org/doi/full/10.10…
<a href="/CanaudLab/">Guillaume Canaud (MD, PhD)</a> <a href="/morin_gbrl/">Gabriel Morin</a> <a href="/EmboMolMed/">EMBO Mol. Medicine</a>
INEM NECKER (@neckerinem) 's Twitter Profile Photo

🚨 We're hiring! The IMMEDIAB Lab team is looking for: 🧪 1 Postdoc 🧬 1 Research Assistant / Bioinfo/ Tech 📍 Paris | Start Sept 2025 📄 Full details + apply: institut-necker-enfants-malades.fr/careers Dr. Fawaz Alzaid

🚨 We're hiring! The <a href="/ImmediabL/">IMMEDIAB Lab</a> team is looking for:
🧪 1 Postdoc
🧬 1 Research Assistant / Bioinfo/ Tech
📍 Paris | Start Sept 2025
📄 Full details + apply: institut-necker-enfants-malades.fr/careers
<a href="/DrFAlzaid/">Dr. Fawaz Alzaid</a>
INEM NECKER (@neckerinem) 's Twitter Profile Photo

🗓️ Join us on Friday, June 6, for a #seminar with Elvira Mass, Head of the Department of Developmental Biology of the Immune System at LIMES Institute Bonn. Prof. Mass will explore the developmental programming of tissue-resident macrophages. Don’t miss it! Nicolas Venteclef IMMEDIAB Lab

🗓️ Join us on Friday, June 6, for a #seminar with Elvira Mass, Head of the Department of Developmental Biology of the Immune System at <a href="/LIMES_Bonn/">LIMES Institute Bonn</a>.
Prof. Mass will explore the developmental programming of tissue-resident macrophages. Don’t miss it!
<a href="/VenteclefNicol1/">Nicolas Venteclef</a> <a href="/ImmediabL/">IMMEDIAB Lab</a>
INEM NECKER (@neckerinem) 's Twitter Profile Photo

🗓️ Join us on June 13, for a #seminar with Han Li, Principal Investigator and leader of the cellular plasticity in age-related pathologies group at Institut Pasteur. Prof. Li will explore senescence induced-cellular plasticity in health & disease. Don’t miss it! Pende Mario

🗓️ Join us on June 13, for a #seminar with Han Li, Principal Investigator and leader of the cellular plasticity in age-related pathologies group at Institut Pasteur. Prof. Li will explore senescence induced-cellular plasticity in health &amp; disease. Don’t miss it! <a href="/MarioPende/">Pende Mario</a>
INEM NECKER (@neckerinem) 's Twitter Profile Photo

🚨 We're hiring at INEM! The Immunity in Health and Disease team, led by Simon Fillatreau, is recruiting: 🔬 Assistant Engineer 🧑‍💼 Horizon Europe Project Manager (ARTiDe project) More info & how to apply: 🔗 institut-necker-enfants-malades.fr/offre-demploi/… 🔗 institut-necker-enfants-malades.fr/offre-demploi/… Inserm

INEM NECKER (@neckerinem) 's Twitter Profile Photo

🗓️ Join us on June 20, for a #seminar with Jean-Emmanuel Sarry Sarry Lab, team leader at CRCT-Oncopole. Dr. Sarry will explore Mitohormesis and metabolic adaptations in response to therapeutic stress in acute myeloid leukemia. Don’t miss it!

🗓️ Join us on June 20, for a #seminar with Jean-Emmanuel Sarry <a href="/jeansarry/">Sarry Lab</a>, team leader at  <a href="/crctoncopole/">CRCT-Oncopole</a>. Dr. Sarry will explore Mitohormesis and metabolic adaptations in response to therapeutic stress in acute myeloid leukemia. Don’t miss it!
INEM NECKER (@neckerinem) 's Twitter Profile Photo

[PUBLICATION] First report of successful pregnancies after treatment with alpelisib for PIK3CA-related overgrowth spectrum. ➡️Fertility preserved ➡️No embryotoxicity ➡️Disease remained responsive after treatment pause 📖Details here: nature.com/articles/s4143…

[PUBLICATION] First report of successful pregnancies after treatment with alpelisib for PIK3CA-related overgrowth spectrum.

➡️Fertility preserved
➡️No embryotoxicity
➡️Disease remained responsive after treatment pause

📖Details here: nature.com/articles/s4143…
INEM NECKER (@neckerinem) 's Twitter Profile Photo

[PUBLICATION] mTORC1 governs multiciliated cell differentiation by favoring progression through a cell cycle variant without DNA replication and by acting on cytolinker proteins for centriole disjunction. 📖Read more: embopress.org/doi/full/10.10… Pende Mario

[PUBLICATION] mTORC1 governs multiciliated cell differentiation by favoring progression through a cell cycle variant without DNA replication and by acting on cytolinker proteins for centriole disjunction.

📖Read more: embopress.org/doi/full/10.10…
<a href="/MarioPende/">Pende Mario</a>
INEM NECKER (@neckerinem) 's Twitter Profile Photo

🗓️ Join us on July 4, for a #seminar with David Sabatini, group leader at IOCB Prague. Dr. Sabatini will explore nutrient sensing by the mTOR pathway. Don’t miss it! Pende Mario

🗓️ Join us on July 4, for a #seminar with David Sabatini, group leader at <a href="/IOCBPrague/">IOCB Prague</a>.
Dr. Sabatini will explore nutrient sensing by the mTOR pathway. Don’t miss it! <a href="/MarioPende/">Pende Mario</a>
INEM NECKER (@neckerinem) 's Twitter Profile Photo

[PUBLICATION] PIK3CA mutations in Schwann cells trigger neuropathy by disrupting nearby healthy tissues. This non-cell autonomous effect shifts local metabolism toward aerobic glycolysis. Early alpelisib treatment is key | PNASNews 🔗pnas.org/doi/10.1073/pn… Guillaume Canaud (MD, PhD)

[PUBLICATION] PIK3CA mutations in Schwann cells trigger neuropathy by disrupting nearby healthy tissues. This non-cell autonomous effect shifts local metabolism toward aerobic glycolysis. Early alpelisib treatment is key | <a href="/PNASNews/">PNASNews</a> 
🔗pnas.org/doi/10.1073/pn…
<a href="/CanaudLab/">Guillaume Canaud (MD, PhD)</a>
INEM NECKER (@neckerinem) 's Twitter Profile Photo

[PUBLICATION] New study with the Bharat lab MRC-LMB Cell Biology reveals the structure of the Neisseria meningitidis filamentous phage MDAΦ. Cryo-EM/ET show how phage bundling supports biofilm formation & pathogenesis. Mathieu Coureuil PNASNews pnas.org/doi/10.1073/pn…

[PUBLICATION] New study with the Bharat lab <a href="/CellBiol_MRCLMB/">MRC-LMB Cell Biology</a> reveals the structure of the Neisseria meningitidis filamentous phage MDAΦ.
Cryo-EM/ET show how phage bundling supports biofilm formation &amp; pathogenesis.
<a href="/MathieuCoureuil/">Mathieu Coureuil</a> <a href="/PNASNews/">PNASNews</a>

pnas.org/doi/10.1073/pn…
INEM NECKER (@neckerinem) 's Twitter Profile Photo

🚨 We're hiring! INEM is recruiting a Group Leader in #Immunology. Join a vibrant biomedical research institute with strong clinical & academic links. 🗓 Apply by Sept 20, 2025 🔗 More info: institut-necker-enfants-malades.fr/careers

🚨 We're hiring! INEM is recruiting a Group Leader in #Immunology. Join a vibrant biomedical research institute with strong clinical &amp; academic links.

🗓 Apply by Sept 20, 2025

🔗 More info: institut-necker-enfants-malades.fr/careers
INEM NECKER (@neckerinem) 's Twitter Profile Photo

[CAREER] A 3-year PhD position is open in Paris to explore how air pollution contributes to CKD. The project combines experimental and environmental science and is hosted by INEM & LISA. 📨 Apply by Sept 1. 🟢 Start Nov–Dec 2025. institut-necker-enfants-malades.fr/offre-demploi/…

[CAREER] A 3-year PhD position is open in Paris to explore how air pollution contributes to CKD. The project combines experimental and environmental science and is hosted by INEM &amp; LISA.

📨 Apply by Sept 1.
🟢 Start Nov–Dec 2025.
institut-necker-enfants-malades.fr/offre-demploi/…
INEM NECKER (@neckerinem) 's Twitter Profile Photo

#France2030 | Félicitations à Guillaume Canaud Guillaume Canaud (MD, PhD), lauréat d’une Chaire d’excellence en Biologie/Santé pour son projet sur les malformations vasculaires liées à KRAS. 🎯Objectif : développer des thérapies ciblées pour une médecine ultra personnalisée. 👏🏼

CFATG (@cfatg) 's Twitter Profile Photo

🎉 Congratulations to Juliane Da Graça, recipient of the 2025 Beth Levine #ThesisPrize! Her outstanding research Morel Lab🇪🇺 on the role of ER/Endosome contact sites in the regulation of #autophagy captures the award's spirit of excellence and innovation. 👏

🎉 Congratulations to <a href="/JulianeDaGraca/">Juliane Da Graça</a>, recipient of the 2025 Beth Levine #ThesisPrize! Her outstanding research <a href="/MEMBRAMICS_lab/">Morel Lab🇪🇺</a> on the role of ER/Endosome contact sites in the regulation of #autophagy captures the award's spirit of excellence and innovation. 👏
INEM NECKER (@neckerinem) 's Twitter Profile Photo

👏🏼 Proud to see Juliane Da Graça, former PhD student at INEM, honored with the 2025 Beth Levine Thesis Prize for her outstanding work on autophagy, supervised by Etienne Morel Morel Lab🇪🇺.

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[PUBLICATION] The Morel Lab🇪🇺 shows how Influenza A virus rewires ER lipid metabolism to promote viral ribonucleoproteins egress. 🦠 📖 journals.plos.org/plosbiology/ar… Carla Alemany Juliane Da Graça sharing the first authorship 👏🏼 w/ Institut Pasteur, since 1887 & IPNP PLOS Biology

[PUBLICATION] The <a href="/MEMBRAMICS_lab/">Morel Lab🇪🇺</a> shows how Influenza A virus rewires ER lipid metabolism to promote viral ribonucleoproteins egress. 🦠

📖 journals.plos.org/plosbiology/ar…
Carla Alemany <a href="/JulianeDaGraca/">Juliane Da Graça</a> sharing the first authorship 👏🏼

w/ <a href="/institutpasteur/">Institut Pasteur, since 1887</a>  &amp; IPNP
<a href="/PLOSBiology/">PLOS Biology</a>