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We've been relying so much on the previous scRNA-seq atlas from Pijuan-Sala et al. as an in vivo reference to analyze gastruloids, thrilled to soon be able to dwelve into the matched spatial data!

New #cellpose release v0.6! Now with a #pytorch 🔥 backend, in addition to #mxnet. pip install cellpose --upgrade, or try an example colab notebook here: colab.research.google.com/github/MouseLa….

2020 was not a great year for concerts, so we had to adapt a bit... but here it is, glad to share our latest production (recorded during lockdown 🙄) with the EPFL Bigband ! #scientists #Jazz youtu.be/CEKV1i8hcVY

Check out our latest preprint on next-gen. #embryoids that combine features of #gastruloids and ETS embryos. Generation of brain-like tissues from epithelialized aggregates. Great work by Mehmet Girgin Nicolas Broguiere and thanks for collaboration Alfonso Martinez Arias. biorxiv.org/content/10.110…

We are happy to share our recent preprint on bioengineered #embryoids formed from embryonic and extra-embryonic stem cells! We study the role of epithelium in gastrulation and formation of brain-like tissues! Follow up to see how we do it: ⬇️ biorxiv.org/content/10.110…

The sheep trials for in situ cartilage refeneration with the HA-TG gels I developed during my PhD. Long term study, glad to see it finally out. Large variability, but better regen on average, and great looking cartilage when things go well !

Excited to see this published!! Great effort by hugely talented Matthias Lutolf PhD student Moritz Hofer 👍🙏

Another very cool follow-up on the factor XIII cross-linked hyaluronan (HA-TG): combination with poly(GlcNAc) nanofibers to make it printable, post-printing enzyme activation for x-linking, & biofabrication of auricular cartilage! Congrats Philipp Fisch onlinelibrary.wiley.com/doi/10.1002/ad…

A calcium‐triggered enzymatic crosslinking mechanism gives this bioprinted ear the rigidity it needs to withstand repeated deformations. Marcy Zenobi-Wong Nicolas Broguiere Philipp Fisch ETH Zurich Read the article: ow.ly/Rwyx50DP2Hz

Modelling embryonic blood development in #gastruloids? We think it looks promising: biorxiv.org/content/10.110… Follow-up study from our recent cardiogenesis work (cell.com/cell-stem-cell…). Nice team effort by Giuliana Rossi sBengali Tania Hübscher 👏👍!

So proud of my auntie Dominique Broguiere and her colleagues for making the world dream again with another historic black hole pic, this time with the magnetic field! 😍

Check out our preprint on #tumoroids: A robust and scalable microwell assay to measure how T cells can kill #tumoroids - patient-derived and fully autologous. biorxiv.org/cgi/content/sh… Nice work by #tumoroid team Devanjali Dutta (DJ), Francois Rivest, L. Francisco Lorenzo Martín, Nicolas Broguiere.

Studying the conditions that favor brain apparition in gastruloids. Congrats Mehmet!

Formation of #gastruloids with anterior neural tissues by inhibition of WNT signaling Congrats to Mehmet Girgin Nicolas Broguiere! sciencedirect.com/science/articl…

Antibacterial, biocompatible and strongly adhesive to cartilage! Check our latest work on development of a novel FXIII cross-linkable chitosan derivative to serve as an injectable adhesive. Nicolas Broguiere Marcy Zenobi-Wong #bioadhesive #hydrogel #chitosan pubs.acs.org/doi/10.1021/ac…

If you're a fan of beautiful figures and a very interesting perspective on in vitro cancer models, check out this new review!

Check out our recent paper on next-generation #gastruloids. Congrats to Mehmet Girgin 👏🎉🥳 and thanks to Nicolas Broguiere Alfonso Martinez Arias SUN bioscience!

We are looking for a highly motivated Postdoc with experience and interest in developmental biology/stem cell/organoid biology, to join our team at the Roche Institute for Translational Bioengineering in Basel! roche.com/careers/jobs/j…

Another step toward replacing Matrigel? Excited to see this paper published! nature.com/articles/s4156… Great work by PhD students antonius chrisnandy & Delphine Blondel👏 Thanks to co-authors Saba Rezakhani Nicolas Broguiere & support from NCCR Bio-Inspired Materials & EPFL Life Sciences #LowonMatrigelhighonPEG

Wonder how much colorectal cancer organoids could be improved by reconstructing the tumor microenvironment? Check out our latest pre-print and opus magnum by Nicolas Broguiere and colleagues!