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I am excited to share this work that spans multiple disciplines to reveal a fascinating observation—ADAR1 mediated RNA editing as a causal mechanism of coronary artery disease. From genetics to RNA biology with real translational potential. Check it out! biorxiv.org/content/10.110…

Excited to share our new findings on loss of Y chromosome affecting cardiovascular outcome in patients with chronic kidney disease 😀 special thx to our nephrologist T. Speer 👍🍀 DZHK Germany Stefanie Dimmeler CPI European Research Council (ERC) @FaiezZannad Caitlyn Vlasschaert Lars Forsberg

Proud to be part of the study showing that loss of the Y chromosome in peripheral blood cells affects cardiovascular disease in patients with chronic kidney disease published Circulation 😀It is amazing to see how much the Y chromosome influences cardiovascular disease.

The long noncoding RNA HEAT4 (heart-failure associated transcript 4) as a target to control monocyte-mediated myocardial injury. Jasmin M. Kneuer Niels Boeckel ahajournals.org/doi/abs/10.116…

Nächste Woche startet der #ESCCongress der European Society of Cardiology. Die wichtigsten Neuigkeiten gibt es im #Livestream vom #LeipzigerKardiologengespräch. 📅 Mi, 04. Sept 2024 | 19:00 - 20:30 Uhr | Livestream 📺herzmedizin.de/kongress-updat… #Herzmedizinde #DGK #BNK

Check out our new human #stemcell based live tracking tool which sorts replicating cells in real-time! Now we can screen #regenerative drugs promoting #cardiomyocyte #proliferation and improve #cardiac function! Thum Lab Thomas Thum Arbeitsgruppe Kardiovaskuläre Regeneration (AG 31) academic.oup.com/cardiovascres/…

Congrats to my friend and colleague Guosong Hong for his stunning and original discovery, published today in Science, on clearing tissues *in living animals* with a common food dye! The dye is tartrazine, used in Doritos! science.org/doi/10.1126/sc…

Excellent work, published by Joerg Heineken and group on two important lncrnas Gadlor1+2 in the cardiovascular system! Congratulations 🎉

Important work by Eric Van Nostrand and Whipplelab identifying snoRNA-associating proteins by eCLIP ! Kudos to all authors! biorxiv.org/content/10.110…

Happy to contribute to this paper on #cardiac #regeneration w/ Bernhard Haubner, Thomas Schuetz & Erika Hilbold. We show the KD of Igfr1 leads to #fibrotic scarring of the neonatal #heart limiting #regeneration #potential Thum Lab Arbeitsgruppe Kardiovaskuläre Regeneration (AG 31) @MHH_life doi.org/10.1038/s41598…

🏅Der #Nobelpreis in Medizin 2024 geht an V. Ambros & G. Ruvkun für ihre Entdeckung der microRNAs (#miRNA)! Diese bahnbrechende Forschung hat enorme Bedeutung für das Verständnis kardiovaskulärer Erkrankungen. Überblick von PD Dr. Niels Boeckel: ➡️ herzmedizin.de/fuer-aerzte-un… #DGK

Two nature papers on macrophage action in heart failure! Wohoo and congratulations Kory and Deepak! doi.org/10.1038/s41586… doi.org/10.1038/s41586…

Really looking forward to the exciting talks!

Happening TODAY! #EVBOSeminarSeries Moderated by Bilal Sheikh. Speakers: Steven Proulx and Lisa Becker. ⏰When: When: Tuesday 29th October 2024. Place: online. See you there! For registration evbo.org

bsky.app/profile/nielsb…

1. What are the benefits and risks of GLP1? Our new study in @naturemedicine comprehensively maps all the benefits and risks of GLP-1 receptor agonists (GLP-1) (Ozempic, Wegovy, Mounjaro, Zepbound). By Yan Xie, Taeyoung Choi and me 🧵 nature.com/articles/s4159…

Can targeting VEGFB turn the clock back in #cardiovascular ageing?⏰ New study in #CardiovascularResearch shows Vegfb186 overexpression by #gene transfer partially reverses age-related #cardiac pathologies such as diastolic dysfunction & #fibrosis academic.oup.com/cardiovascres/… #CVD

What a proud moment to see my very first last-author paper being published at #cardiovascularResearch Thank you so much to Stefanie Dimmeler and Nivethitha Manickam and all the contributing authors for making this happen.

🚨 Out now in Circulation Research 🚨 So proud with Maria Kontaridis to launch this Compendium on Interorgan Crosstalk in Heart Failure & Cardiometabolic Disease. Heart failure it’s systemic. Multiorgan. Dynamic. Circulation Research DZHK Germany Deutsches Herzzentrum der Charité Max Delbrück Center

Finally, in review #4 Dunja Aksentijevic Ricciarelli Simon Sedej Paillard Mélanie Katrin Streckfuss-Bömeke EdoardoBertero Jeremy Fauconnier et al discuss how the imbalance between mechanical load and mitochondrial ATP supply induces a redox mismatch that drives #heartfailure progression. nature.com/articles/s4156…