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The Shriners Children's State of Science meeting was held last week. Marquette & MCW Joint Dept. of Biomedical Eng. students shared updates on our foot & ankle work, including some exciting new weightbearing CT work and collaborators from UNT shared work using machine learning to better utilize motion analysis data.

We’ve created a new field called “chronogenetics”: controlling gene expression with the cell’s internal clock! Lara Pferdehirt & Anna Damato made living implants that sync to the body and automatically deliver biological drugs on a 24 hr cycle. nature.com/articles/s4146…

Engineered stem cells automatically deliver arthritis drugs at prescribed times of day apnews.com/press-release/… nature.com/articles/s4146…

Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068) chng.it/q4D5Rc9v6W via Change.org

Shriners Children’s recently hosted more than 130 physicians, clinicians, data scientists, engineers, and researchers from across the country at the “Shriners Children’s State of Research: Special Emphasis on Muscle and Bone Health” at Shriners Children's Chicago.

Excited for our workshop on interdisciplinary solutions to study mechanisms of musculoskeletal pain at #USASP2025 in Chicago, featuring talks from Nadeen Chahine, Hang Lin, Rachel Miller (C-COMP), and Allan Basbaum (UCSF Dept. of Anatomy) US Association for the Study of Pain. Would love to see you there!

We are excited to invite all MSK researchers in the US midwest to join us for our annual Research Symposium in Saint Louis May 21. Faculty, postdocs, students are welcome. Registration is free! musculoskeletal.wustl.edu/education-2/sy… WashU Biomedical Engineering WashU Medicine Division of Bone & Mineral Diseases WashU Medicine Saint Louis University Mizzou

📢 ORS Call for Volunteers! Make an impact in #orthopaedicresearch by joining a committee, becoming a section representative, reviewing journal articles, supporting ORS events, and much more! Learn more and apply today: ors.org/volunteer/

Excited for our most recent publication mapping macrophage populations in the synovium with knee injury and obesity! Great work by Natalia Harasymowicz and team!

Congrats Dr. Jackie Garcia on an amazing dissertation on defense "Characterizing PIEZO1 Mechanotransduction in Articular Chondrocytes"! The Guilak Lab WashU DBBS

📢 ORS Call for Volunteers! Make an impact in #orthopaedicresearch by joining a committee, becoming a section representative, reviewing journal articles, supporting ORS events, and much more! Learn more and apply today: ors.org/volunteer/

Excited to share the latest chapter of our work on fat-joint interorgan crosstalk in knee OA, featuring the role of complement factor D secreted by fat in knee pain. Link here: bit.ly/42Og5hJ Thanks to Farshid Guilak The Guilak Lab, Hope Welhaven, PhD Ron June and all coauthors!

Congrats to Sophie Paradi on a fantastic Master's thesis and defense! WashU McKelvey Engineering WashU Biomedical Engineering. Amazing work and collaboration with Erica Ely and many others in The Guilak Lab

science.org/doi/full/10.11… May 12th C-COMP journal club with Kelsey Collins and Farshid Guilak. They will discuss their exciting new paper at 10amCST. We will send a link upon request

As of today Columbia University has not received ANY of the terminated funding and many non-competitive renewal of federal grants. Therefore, last week the university starting laying off postdocs. If you care about PANDAS research please support my postdoc joinus.cuimc.columbia.edu/index.cfm?fuse…

Congrats to Amanda Cimino for her latest paper creating a chronogenetic gene circuit that automatically delivers anti-inflammatory biologic drugs in response to inflammation or circadian signal! jbioleng.biomedcentral.com/articles/10.11…

Most studies of cartilage mechanobiology study the upregulation of chondrocyte gene expression and biosynthesis with mechanical loading. Check out our recent paper where Daniel Palmer studied the down-regulated "mechanome" with Piezo1 or TRPV4 activation. tandfonline.com/doi/full/10.10…

Join us June 11 for #WebinarWednesday, Session 2 of our summer series on compassionate leadership. Dr. Anne Welsh will share how to lead with confidence, empathy, and purpose, even under pressure. Learn more, watch session 1, and register for session 2: bit.ly/3XzipIA

Huge congrats to Dr. Amanda Cimino for an outstanding presentation and defense - her committee said it was time for a "PhD+" degree. Amazing work!

Congrats to Amanda Cimino and team on her latest paper in J Controlled Release - she developed new synthetic chronogenetic gene circuits that allow controlled drug delivery at precise times day using various elements of the circadian clock! doi.org/10.1016/j.jcon…