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Molecular and spatial analysis of ganglion cells on retinal flatmounts: diversity, topography, and perivascularity biorxiv.org/cgi/content/sh… #biorxiv_neursci

Afadin Sorts Different Retinal Neuron Types into Accurate Cellular Layers biorxiv.org/cgi/content/sh… #biorxiv_neursci

Genetic and pharmacological correction of impaired mitophagy in retinal ganglion cells rescues glaucomatous neurodegeneration biorxiv.org/content/10.110… #biorxiv_neursci

Predicting the Regenerative Potential of Retinal Ganglion Cells Based on Developmental Growth Trajectories biorxiv.org/content/10.110… #biorxiv_neursci

Production of clinical grade patient iPSC-derived 3D retinal organoids containing transplantable photoreceptor cells biorxiv.org/content/10.110… #biorxiv_neursci

We have innovated design of templates for CRISPR/Cas9 editing which allows efficient introduction of epitope tags in vivo. It is a simple hack which we hope to be broadly useful. Work by talented graduate student Chuanping Zhao. nature.com/articles/s4146…

I will be presenting our work ‘A genome-wide in vivo CRISPR knockout screen identifies neuroprotective targets in retinal degeneration’ at #ARVO2025 at 11:30-11:45 am, May 7, welcome to visit and look forward to your feedback!

A new combination technique enables DNA sequencing and high-resolution imaging in intact cells — offering new insights into progeria and aging. broad.io/expansion-in-s… Jason Buenrostro Fei Chen Lab Ajay Labade Caroline Comenho zack chiang Science Magazine

Administration of barcoded AAV capsid library to the putamen of non-human primates identifies variants with efficient retrograde ... biorxiv.org/content/10.110… #biorxiv_neursci