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Pre-print: nanopore seq of xeno-nucleic acids (unnatural base pairs Ubp). We built all single-Ubp 6-mers, demo-ed new strategy of splicing nanopore raw signals for a more accurate (>80%) and specific (99%) base caller. Collab: Niranjan Nagarajan & Hirao labs biorxiv.org/content/10.110…

Over the past few decades, it has become increasingly clear that epigenetic and epitranscriptomic modifications are crucial in regulating a wide range of functions across all forms of life. These modifications affect major biological processes, including those responsible for

Just out in Cell: the Asian Immune Diversity Atlas (AIDA) is a 5-nation single-cell blood atlas. We show that humans are remarkably diverse in gene expression and cell phenotype, with disease implications #healthcaredisparities #PrecisionMedicine [tinyurl.com/AIDA-Cell-2025]. [1/14]

cell.com/cell-reports-m… Excited to share this latest study from the lab. Kudos to Shumei and the team on establishing a precision oncology paradigm (CAN-Scan) with real-world impact and significance for colorectal cancer patients in the clinic.

It’s the culmination of a long, dedicated journey—a true labor of love involving a monumental amount of work, and the result of a global team effort, to realize a vision for phenotype-driven precision oncology that we set in motion over 9 yrs ago!

Thrilled to share our latest collaboration with Ramanuj Dasgupta's lab! Chayaporn Nok Suphavilai Rafael Peres CAN-Scan: A multi-omic phenotype-driven precision oncology platform identifies prognostic biomarkers of therapy response for colorectal cancer: Cell Reports Medicine cell.com/cell-reports-m…

Did you know the secret to a vibrant old age might be living right inside you?🤔 A study from A*STAR Genome Institute of Singapore (A*STAR GIS) led by Niranjan Nagarajan, Aarthi Ravikrishnan, indrik wijaya, reveals how our gut microbes 🦠 play a crucial role in healthy aging! Learn how these tiny neighbours can keep our golden

Huge effort by Cherry Chengchen Li 李成辰 + Aarthi Ravikrishnan and exciting collaboration with Minghao Chia John Common Viduthalai Rasheedkhan Regina, the HELIOS team and many others!

Folks, a historic first Human Cell Atlas General Meeting in Singapore - the place where single cells meet their match! Late bird registration never closes. But the meeting starts on June 9, so that’s your final deadline … See you at #HCA2025GM

🚨 Aging and Microbiome Conference 2025 📌 Jena, Germany 📆 October 28-29, 2025 ⏰ Abstract submission deadline: 31.05.2025 ℹ️ amc25.leibniz-fli.de

Out Now! Guidelines for preventing and reporting contamination in low-biomass microbiome studies bit.ly/4jYYqu4 #Microbiome #Contamination #Biomass

🔬Low on microbes, high on challenges!🔬 Studying low-biomass environments in microbiome research? The struggle is real when it comes to contamination! Even the tiniest sprinkle of external microbes can throw off your results, making traditional methods a no-go. That's why the

Funny how @nature publishes a commentary like this, but the journal itself refuses to publish negative results except through a byzantine 'matters arising' process that takes years nature.com/articles/d4158…

Direct sequencing of unnatural xeno-nucleic acids beyond DNA RNA. Out at Nature Communications Now you can seq non canonical bases easily on Oxford Nanopore Highlights in XNA synthesis and assembly, seq trace splicing/stitching, model training, usage… Collab Hirao, Niranjan Nagarajan labs