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.No Priors with Luis von Ahn founder of Duolingo Topics: *gaming as the future of education *motivation as the hard problem of learning *going ai-native *unhinged brand *duolingo for chess, math and more languages

In biotech, a small number of disease areas are focused on due to industry structure (many companies are incubated by VCs, who flip them pre-product into the pipelines of a handful of pharmas) This means a lot of big, impactful areas are completely ignored and unfunded Here are

upcoming guests: - AlphaEvolve (DeepMind) team - Fei-Fei Li, World Labs - Qasar Younis, Applied Intuition - Ben Mann, Anthropic - Varun Mohan, Windsurf

new No Priors with the legendary Fei-Fei Li! topics: why she’s building world labs missing gaps in the AI future robotics and physical intelligence greatest challenges of 3D her PhD, ImageNet advising sensei Karpathy importance of human-centered AI

🎙️ No Priors w Fei-Fei Li *Why she’s building world labs *Missing gaps in the AI future *Robotics and physical intelligence *Greatest challenges of 3D her PhD, ImageNet *Advising Andrej Karpathy *Importance of human-centered AI youtube.com/watch?v=C6Zm5S…

New episode drop: Ben Mann, cofounder Anthropic - Claude 4 launch - what happens when you act like tokens are free - MCP - specialization and the future of models - safety for agents - economic turing tests

.Anthropic founder Ben Mann on whether Claude Code competes with Anthropic’s own codegen model API customers:

New No Priors w Qasar Younis & Peter of Applied Intuition *World's most underhyped AI company? *Urban design & autos *Moving industrial back to USA? 🇺🇸 *Hardware replaced by software in cars *Big picture future

Congratulations team Harvey! AI progresses at a different pace

New No Priors with Pushmeet Kohli Matej Balog from DeepMind AlphaEvolve on: *ai co-scientists *improving matrix multiplication *reclaiming ~1% of google compute *can AI discover new knowledge? *evolutionary algorithms

Our LLM based agents like AlphaEvolve, Google Co-scientist and Project Naptime enable a dramatic step change in performance across Science, Coding and Cybersecurity. The awe-inspiring effectiveness of agentic frameworks will drive a lot of progress in the coming years.

Frank Slootman is corporate David Goggins - I love it.

what's next in getting to zero-shot AI-designed antibodies in clinic? Joshua Meier at Chai Discovery on other properties:

New No Priors: Parker Conrad, one of tech's most admired founders: *his redemption arc *why you shouldn't start a company *why the conventional wisdom on "point product" is bad *founder psychology *building a team of owners *the impact of AI on SaaS strategy *will Rippling be

.Parker Conrad on "AI rollups" and how he developed an allergy to ops at Zenefits: "it's very hard to replace ops with software after you've scaled it up"