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Excited to be moving HOME to NYC to head the Laboratory of Environmental Microbiology Rockefeller University in Jan. 2025. Pics surely representative of future lab activities.

Evolution and origins of rubisco cell.com/current-biolog… Current Biology

This technique is amazing and figure 3 is insane!

Enhancing Photosynthesis under Salt Stress via Directed Evolution in Cyanobacteria biorxiv.org/content/10.110…

It's been really fun watching Alex piece this result together, I think we're going to be surprised again by this system as we learn more about it.

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Our latest preprint: Sriram Garg calculate a general substitution matrix for structural phylogenetics and used it to root the tree of life. biorxiv.org/content/10.110… 1/n

Genome-Scale Metabolic Model Reconstruction and Investigation into the Fluxome of the Fast-Growing Cyanobacterium Synechococcus sp. PCC 11901 | ACS Synthetic Biology pubs.acs.org/doi/10.1021/ac… ACS Synthetic Bio

Our paper out today @nature: phages reconstitute NAD+ to counter bacterial immunity Phaged invented a new biochemical pathway for NAD+ synthesis - including previously unknown enzymatic reactions - to evade bacterial defenses Congrats Ilya Osterman! nature.com/articles/s4158…

Congrats Yuichi FURUHATA and team for streamlining yeast genetic code expansion through OrthoRep-driven evolution of aaRSs. Several evolved aaRSs give high translational efficiency with unnatural amino acids. A neat self-regulating aaRS is also found. biorxiv.org/content/10.110…

Well, it seems I am officially a published scientist 🥳🙌🏻👩🏻‍💻 Thanks Luke Mackinder and team for supporting me! This work on diatom pyrenoids is interesting and exciting - definitely take a look (especially figure 4b 😉) Cell

A promiscuous algal Rubisco binding protein that binds to the large subunit, can condense plant Rubiscos and functionally complement an epyc1 mutant. Congrats James Barrett + great team effort Mihris Ibnu Saleem,Michael Plevin,McCormick Lab,Jamie Blaza,Peter O'Toole. doi.org/10.1038/s41477…

🧵 Really excited to share our new paper! As species diversify, sex pheromones rapidly change, but how do male mating circuits co-evolve to guide mate choice? A thread on circuit evolution & mating strategy... 1/9 nature.com/articles/s4158…

🦠🧬Our paper is live Cell: Genome integrity sensing by the broad-spectrum Hachiman antiphage defense complex authors.elsevier.com/sd/article/S00… Through structural, genetic and microbiological approaches, we show that Hachiman degrades DNA… by sensing low integrity DNA.

It's been so fun watching this story develop, really great to see it out. As each defense system gets understood we get to learn another solution to the problem of bacterial immunity and bacteria never disappoint in their creativity.

No, you’re not seeing double. This creature called a sea walnut does indeed have two mouths and two “rear” ends. Yet, it wasn’t born with these double features: Researchers have shown they can make two sea walnuts readily fuse into one body. The finding suggests that this group

Obituary of Bruce Ames, who developed the Ames test and thus likely saved many lives. Bruce passed away in Berkeley on October 5th. berkeleyside.org/2024/10/28/bru…

Unique biogenesis and kinetics of hornwort Rubiscos revealed by synthetic biology systems: Molecular Plant cell.com/molecular-plan… Molecular Plant & Plant Communications

Congrats to the team for this incredibly bizarre and perplexing result. Leaving out a chaperone causes hornwort rubisco to be formed in a stalled folding intermediate...which is substantially _faster_ than the normal fold???

My first Laura Gunn collab with Fay-Wei Li 李飛葦 research article is out @mplantpcom ! Using SynBio approaches we found a new Rubisco assembly intermediate and successfully express hornwort Rubisco in E.coli. 1/3 cell.com/molecular-plan…