
Novartis Science
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https://www.novartis.com/research-development/biomedical-research 24-12-2013 17:12:27
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I’m excited to share that we’re entering a strategic research collaboration with Isomorphic Labs to use state-of-the-art #AI technologies—including the next-gen model of AlphaFold—to discover novel small molecule therapeutics for select biological targets. storage.googleapis.com/isomorphiclabs…




Yesterday, Novartis and Medicines for Malaria Venture (MMV) announced positive data from the CALINA study exploring a potential medicine formulated for the smallest babies with #malaria, for whom there is currently no evidence-based treatment.


In APL Bioengineering, Novartis researchers unveil a new device that enables high-throughput screening of stretched cells to better understand how they respond under mechanical stress and inform drug discovery. #mechanobiology

Our researchers share a new approach for the potential treatment of #sicklecelldisease: using molecular glue degraders to break down a novel protein that suppresses fetal hemoglobin levels. Read their paper in Science Magazine




The President of Novartis Biomedical Research, Fiona Marshall, talks about curiosity and collaboration, and her focus on developing “platforms for productivity” that build upon company successes to produce a robust portfolio of medicines for patients. go.novartis.social/4d9PTRQ.

In Nature Microbiology, researchers describe a potential pediatric drug candidate for #cryptosporidiosis, a neglected disease that causes severe diarrhea, prolonged illness, and even death in young children and other vulnerable populations worldwide. novartis.social/6015mxXuX


Novartis Biomedical Research and the University of Dundee Drug Discovery Unit (DDU) are collaborating to advance drugs to help address global health challenges, including an antimalarial that targets dormant parasites, and an anti-viral for pandemic preparedness. novartis.social/6019WG8jN


Novartis, Monte Rosa Therapeutics, Inc announce an exclusive global development and commercialization license agreement to advance molecular glue degraders, including an investigational program currently in Phase 1 clinical development. go.novartis.social/4fgFW6o




Novartis has entered into a global license and collaboration agreement with PTC Therapeutics for a Huntington’s disease program, currently in Phase II development, with the potential to become the first oral disease-modifying therapy for the disorder. go.novartis.social/3Zx6nQf

