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FCP is better for colonic > small bowel (SB) inflammatiin, but how accurate is it in proximal vs. distal SB? Using VCE as gold standard, our Sheba Medical Center brilliant fellow Offir Ukashi reports in Journal of Crohn's and Colitis a dilutional gradient of calpro along the SB ! pubmed.ncbi.nlm.nih.gov/39120437/

Our talented Adam Goldman found increased intest perforations with JAKi class. Examined in Rheum pts to reduce confounding by IBD. Caveat of voluntary reporting,but this is how aTNF TB risk was first found, so cant be lightly discarded. UEGJ pubmed.ncbi.nlm.nih.gov/39736095/

Inter‐Rater Disagreements in Applying the Montreal Classification for Crohn's Disease: The Five‐Nations Survey Study. Offir Ukashi onlinelibrary.wiley.com/doi/full/10.10…

Study by the 🇮🇪🇪🇦🇵🇹🇮🇱🇨🇵 Five-Nations in UEGJ showing that (like most classification systems) actual inter-rater agreement for CD Montreal classification is modest at best. At least LLM and AI models were not much better😉 Uri Kopylov Offir Ukashi doi.org/10.1002/ueg2.1…

Hot off the press. Inter‐Rater Disagreements in Applying the Montreal Classification for Crohn's Disease: The Five‐Nations Survey Study. Uri Kopylov Fernando Magro #henityanai ⁦Offir Ukashi⁩ #5Nationfriendsandparticipants onlinelibrary.wiley.com/doi/10.1002/ue…

Our RCT now in Gastroenterology : Pts with #Crohn in remission, who recieved treat-to-target Tx guided by #capsule endoscopy inflammatory assessment, had a significantly lower flare risk over 24m compared to pts continuing standard care Helmsley Charitable Trust gastrojournal.org/article/S0016-…

Jean-Frederic Colombel Shrinivas Bishu The Lancet Definition of relapse was rather non-standard, and rate of steroid Tx for relapse comparable between arms, as discussed in our Editorial thelancet.com/journals/langa…