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1000 persone a Rimini per la XXII Convention Scientifica di Fondazione Telethon. Più di 500 ricercatori finanziati si confrontano sulle malattie genetiche rare per collaborazioni e fare passi avanti nella ricerca Grazie a Regione Emilia-Romagna inEmiliaRomagna #ConventionFondazioneTelethon

IL-1β+ macrophages and the control of pathogenic inflammation in cancer dlvr.it/TJslPb #immunology

#MustRead. For #TumorImminologyLovers & more, check this fantastic review Renato Ostuni nicoletta caronni &co Trends in Immunology all about #IL1 from #macrophages & pathogenic #inflammation in #cancer. #ScienceMatters dlvr.it/TJslPb

Thank you Renato for a clear and timely review highlighting how IL-1β⁺ macrophages contribute to disease both locally by forming the inflammatory niche and distally ny expanding pathogenic myelopoiesis, highlight their potential as therapeutic targets.

A must-read review on the recent developments in the field that refine our understanding of IL-1 in cancer development and progression: Distinguishing pathogenic inflammation from other signals and knowing when and where it drives disease are essential!

and here's the Sharelink with full access: authors.elsevier.com/a/1ks7s5Eb0R-b…

Review Trends in Immunology nicoletta caronni Renato Ostuni IL-1β+ macrophages and the control of pathogenic inflammation in cancer cell.com/trends/immunol…

🚨 What if a single DNA typo could inflame the body and outcompete healthy blood cells? 🧬 This happens in #VEXAS syndrome. In our paper out today in Nature Medicine we show how. 📖 Here: rb.gy/300drs 👇 A story of inflammation, clonal warfare and #CRISPR editing 🧵

📌Join us at the Italian Outdoor Festival this Sunday! Will speak with Dylan Liabeuf (berlin-barcelona.com) and ultrarunning legend Filippo Canetta about #immunology #running #exercise #Wellness #scicomm Università Vita-Salute San Raffaele Ospedale San Raffaele Fondazione Telethon italianoutdoorfestival.com/event-item/all…

Thank you Renato Ostuni, Filippo and the Italian Outdoor Fest. for organising such a cool and informative event! Last kms of the berlin-barcelona.com initiative. Let's meet in Milan, can't wait: italianoutdoorfestival.com/event-item/all… Charité - Universitätsmedizin Berlin Università Vita-Salute San Raffaele Ospedale San Raffaele Fondazione Telethon

IL-1β+ macrophages and the control of pathogenic inflammation in cancer dlvr.it/TKdqg4

We are looking for 1 mid-career scientist (and postdocs) willing to join us as SR-Tiget in Milan. Basic and translational immunology, gene and cell therapy, genome/protein tech, computational biology... all welcome 💚🤍❤️ check the Call, pls RT! fondazionetelethon.it/en/what-we-do/…

The field of exercise-immuno-oncology is taking off... out now in NEJM "A 3-year structured exercise program initiated soon after adjuvant chemotherapy for colon cancer resulted in significantly longer disease-free survival" nejm.org/doi/full/10.10…

Not just mitosis - the centromere as a site of immune activation 🔥🔥🔥 Viral proteins alter centromere organization and local amplification of DNA -> this is recognized by nuclear cGAS-STING beautiful stuff by Nicolas Manel lab in Cell Press cell.com/cell/fulltext/…

Great piece Miriam Merad, MD, PhD The Wall Street Journal "separate beneficial inflammation, the one that protects us from microbes and from tumors, from the pathogenic inflammation that is enhancing cancer progression, promoting atherosclerosis, promoting damage in the older brain" wsj.com/health/inflamm…

Check this out! Great stuff, as usual from the Iannacone Lab

Neutrophil aficionados, this is THE meeting! Don't miss it🎯

🧵1/ 🚨 Just out in Science Translational Medicine Science Translational Medicine our latest work Luigi NALDINI: We show how tumor-targeted cytokines can rescue CAR-T function and recruit endogenous T cells to fight glioblastoma, the toughest brain cancer. 🔗science.org/doi/10.1126/sc… 👇 Here's a thread:

Out in Science Translational Medicine! The Naldini lab delivers another masterclass of stem/immune cell gene engineering to deliver cytokines in the TME and boost CAR-T cell activity in glioblastoma. Kudos to Federico Rossari @giorgiaalvisi and Nadia Coltella for this important study🔥