
OtonkoskiLab
@otonkoskil
ID: 1001796576761827328
30-05-2018 12:04:51
164 Tweet
463 Followers
160 Following


#ZNF808 is a new AR #MorbidGene for pancreatic agenesis & subsequent neonatal #diabetes. @DrElisaDeFranco Nick Owens Michael Imbeault et. al. in Nature Genetics 👏 👇 nature.com/articles/s4158…

Watch: @DrElisaDeFranco on the ExeterDiabetes team's discovery - a gene that is crucial for the human pancreas, yet does not exist in nearly all other animals. It challenges assumptions about how the regulation of development evolves. Full vid here: news.exeter.ac.uk/faculty-of-hea…






Two of our PI's Jette Lengefeld and Pekka Katajisto presenting in the #ISSCRDigital webinar on Stem Cell Size and Shape on April 2nd. Register now 👇




Very happy to see our long-term project on the functional characterization of an RFX6 mutation enriched in Finns published in Diabetologia. Superb work by Hazem Ibrahim. Read here: rdcu.be/dHX38

News from our CoE by OtonkoskiLab Hazem Ibrahim highlights the role of RFX6 in maintaining pancreatic progenitors and uncovers how RFX6 heterozygous loss-of-function affects beta-cell function, increasing the risk for diabetes Suomen Akatemia | Research Council of Finland University of Helsinki link.springer.com/article/10.100…