
Timo Otonkoski
@otonkoskit
Pediatric endocrinologist and stem cell scientist, director of @STEMMProgram, vice director of @MetaStem_Center, saxophonist, father and grandfather.
ID: 822521035220197376
https://www.helsinki.fi/en/researchgroups/pluripotency-and-disease-modeling 20-01-2017 19:07:51
321 Tweet
805 Followers
195 Following

How are heterozygous carriers of a RFX6 pathogenic variant predisposed to develop diabetes? Do not miss our latest work, where talented Hazem Ibrahim explored the molecular mechanisms behind monogenic diabetes due to RFX6 mutations:


A splice site variant in MADD (a T2D gene) results in reduced beta cell number and increased proinsulin-to-insulin ratio in stem cell derived islets. Beautiful work by Taneli Raivio and colleagues Timo Otonkoski Jonna Saarimäki-Vire , congratulations!



A great start to #EISG2024 in Helsinki with Maike Sander & Lab presenting the latest developments in stem cell islets!






Huge thanks to all participants @eisg2024! It was great to host you all in Helsinki for three days of exciting islet biology, we had a blast! Big kudos to the organizing team Timo Otonkoski @V_Lithovius Jonna Saarimäki-Vire Sachin Muralidharan Hazem Ibrahim Tom Barsby Lindahl Maria Kaisa S


Uusi kuvantamismenetelmä diabeteksen soluhoitojen tehon ja turvallisuuden tutkimiseen. Menetelmän avulla voidaan määrittää siirteiden kokoa ja laatua, mikä parantaa diabeteksen solukorvaushoitojen turvallisuutta ja tehokkuutta. Medicine and Health, University of Helsinki Turun yliopisto - University of Turku helsinki.fi/fi/uutiset/ela…

Suomessa muuta maailmaa yleisempi geenimuunnos heikentää insuliinin eritystä ja lisää riskiä sairastua kakkostyypin diabetekseen sekä raskausdiabetekseen. University of Helsinki Hazem Ibrahim OtonkoskiLab helsinki.fi/fi/uutiset/dia…



Incredible discussion between two experts, the opponent Raphael Scharfmann and the candidate Hazem Ibrahim !


Drumroll, please! 🥁 Announcing #EISG2025 keynote speakers: - Prof. Lori Sussel (Sussel Lab )– Expert in islet biology, uncovering networks for T1D therapies. - Prof. Klaus H. Kaestner (klaus kaestner )– Leader in genetics, islet failure & early T1D events. Don’t miss it
