🚨We are now accepting applications for PNCC's #CryoEM EM School Workshop for August 2023📷 More information: pncc.labworks.org/training/works…

Join us at EM School, a transformative workshop where scientists delve into the fascinating world of #CryoEM. Held 🗓️ August 7th - 18th 2023 From sample prep to data collection, master the entire workflow in just 2 weeks! 🚀 🌍 Open to ALL scientists! PNCC project not required

Mark your calendars 📅! The 2023 Research Services Fair is happening Thursday, October 12, 1-4:30pm Iowa Memorial Union Main Lounge. Learn more and register now: research.uiowa.edu/research-devel…

Processing our first #cryoEM dataset from the Tundra with Falcon-C 👀 Protein & Crystallography Facility

Come see us at the UIowa Research Services Fair this Thursday in the IMU from 1-4:30 PM! Register by today! Carver College of Medicine app.smartsheet.com/b/form/7d474b6…

A monumental work by many in my lab and Protein & Crystallography Facility , and another wonderful collaboration with Pietro Pichierri 🇮🇹🇪🇺 @[email protected] and his team! A double-ring of human RAD52 remodels replication forks restricting fork reversal biorxiv.org/content/10.110… Morteza Nick Schnicker Lokesh Gakhar

1/n: We are excited to share that our paper on Chroma, a general purpose diffusion model for proteins, is out today in nature! nature.com/articles/s4158… A couple of my favorite highlights in the 🧵below 👇

Can you spot the particle that’s ready for the Super Bowl? #negstainTEM UIowa Research 📷: Zhen Xu

SBGrid's eLife paper received a citation in January from Nick Schnicker of University of Iowa in Journal of Virology: Adaptation of SARS-CoV-2 to ACE2H353K mice reveals new spike residues that drive mouse infection. Read more here: buff.ly/490VYP8 #SBGrid #research #structuralbiology

In our newest practical guide, developed with Google DeepMind and EMBL-EBI, delve into the fundamentals of #AlphaFold, explore its strengths and limitations, and gain practical skills through hands-on exercises. Start the free, self-paced tutorial today: ebi.ac.uk/training/onlin…

Soluble α-Klotho (sKLA) exists in multiple conformations, supporting pleiotropic FGFR/FGF23-independent functions. #MassPhotometry revealed sKLA can exist as dimers as well as in complex with FGFR/FGF23. Preprint by Nick Schnicker from Carver College of Medicine et al. doi.org/10.1101/2024.0…

The cover of this month's issue tinyurl.com/yfw9e4xr highlights a review of the role of post-translational modifications in protein structures and their prevalence in the PDB, which also provides examples to serve as valuable references. Read more at tinyurl.com/3rn4ne99

An outlook on structural biology after AlphaFold: tools, limits and perspectives 1. AlphaFold's AI-based tools have revolutionized protein structure prediction, dramatically enhancing accuracy and broadening the scope of accessible structures. 2. The integration of AlphaFold

There is a new tool on BioIcons to turn any protein (in PDB format) into a 2D vector illustration in SVG format. You can upload any PDB file or import from PDB, AlphaFoldDB or ESMFoldDB. Feedback welcome :) bioicons.com/pdb2vector/

Come join the structural biology community this Thursday at 9 am to learn more about the good and bad of #AlphaFold Carver College of Medicine UIowa Research