🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

The Major Histocompatibility Complex (MHC) plays a critical role in immunity. It’s also very unusual, with 1000s of alleles, 1000s of GWAS hits, and trans-species polymorphism (TSP). Just how old is this TSP?? A 🧵 about my new preprint w/Jonathan Pritchard: (1/13) doi.org/10.1101/2022.0…

20th Anniversary of the Center and my employment #CBGM, MCG

Development of a Single Molecule Counting Assay to Differentiate Chromophobe Renal Cancer and Oncocytoma in Clinics mdpi.com/1707590 #mdpicancers via Cancers MDPI

First postdoc paper with the one and only Ruslan Medzhitov is finally out in PNASNews! pnas.org/doi/abs/10.107… We introduce network hypermotifs - higher-order circuits of network motifs (Uri Alon), detect them in real networks and describe their emergent dynamic properties.

Open house tonight! Join us to learn more about our Traditional Residency Program, including our commitment to #DEI & opportunities for advocacy. Meet program leadership, chief residents & current residents of Yale Internal Medicine Chiefs. 💻See you at 7 pm ET: m.yale.edu/openhouse

Check out our latest: Development of a Single Molecule Counting Assay to Differentiate Chromophobe Renal Cancer and Oncocytoma in Clinics. Sharad Purohit Natasha M. Savage @mkterris Sravan Kavuri ow.ly/5bw450KFXlv

Our new publication on establishing role of IL1ra in T1D. Khaled Bin Satter Paul Tran Katherine Richardson, MPH, MS Lynn Tran, @JDRF, #TEDDYStudy, Serum IL-1ra Is Associated with but Has No Genetic Link to Type 1 Diabetes mdpi.com/1826312 #mdpiendocrines via MDPI

The Sriracha founder also won't budge on taste. A supplier once told David Tran that his sauce was too spicy. A friend suggested to “add a tomato base” to make it sweeter. Tran replied: “Hot sauce must be hot. If you don’t like it hot, use less. We don’t make mayonnaise here.”

Grants 😞 Manuscripts 😣 Course evaluations 😫 Rejection is everywhere in academia. But we keep it quiet. Only stories of success get told. So heres a story on rejection: "The potato, the egg and tea bag" Academic Chatter™

10 academic writing skills I wish I had learned as a PhD student (with updated links) A thread ⬇️ 🧵 for PhD students and junior scholars:

In this literature review, we provide developments over the past 15 years on proteogenomic characterizations of clear cell renal carcinoma and their implication for targeted therapy development by incorporating DNA mutations, gene expression, and proteomic signature data.

Our story on nucleotide-decoupled G proteins is now out in Nature Chemical Biology: rdcu.be/c3xKm! Thank you to the Lambert lab members and our collaborators for their invaluable support. Also check out Mikel Garcia-Marcos Laboratory’s News & Views doi.org/10.1038/s41589…!

A 34-year-old female living in the Northeastern U.S. p/w 3 weeks of cough, dizziness, dyspnea, headache & chest pressure. Hx of cough after cleaning a parrot cage at the pet store where she worked. Initial EKG below. Labs & imaging benign. What’s the likely diagnosis? Paul Tran