PRIMED Consortium (@prsdiversity) 's Twitter Profile
PRIMED Consortium

@prsdiversity

The NIH-funded Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium

ID: 1440700196250218505

linkhttps://primedconsortium.org/ calendar_today22-09-2021 15:31:38

226 Tweet

521 Followers

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Pradeep Natarajan (@pnatarajanmd) 's Twitter Profile Photo

Delighted to share our study by Sarah Urbut with Akl Fahed on adding in a CAD polygenic risk score to clinical factors to boost CAD risk prediction, particularly for recovering premature CAD events ahajournals.org/doi/10.1161/CI… Circulation: Genomic and Precision Medicine

Delighted to share our study by <a href="/tigerstatdoc/">Sarah Urbut</a> with <a href="/aklfahed/">Akl Fahed</a> on adding in a CAD polygenic risk score to clinical factors to boost CAD risk prediction, particularly for recovering premature CAD events ahajournals.org/doi/10.1161/CI… <a href="/Circ_Gen/">Circulation: Genomic and Precision Medicine</a>
Pradeep Natarajan (@pnatarajanmd) 's Twitter Profile Photo

Individual polygenic risk scores for the same trait can yield different results due to various derivation differences. Our study led by A. Misra & w Aniruddh Patel demonstrates how successive score integration can improve accuracy & stability nature.com/articles/s4146…

Individual polygenic risk scores for the same trait can yield different results due to various derivation differences. Our study led by A. Misra &amp; w <a href="/AniruddhPatelMD/">Aniruddh Patel</a> demonstrates how successive score integration can improve accuracy &amp; stability nature.com/articles/s4146…
Pradeep Natarajan (@pnatarajanmd) 's Twitter Profile Photo

Terrific work from Iftikhar J. Kullo. *10y* fu MI-GENES trial (ahajournals.org/doi/10.1161/CI… Circulation) now shows that CAD PRS disclosure vs not on top of clinical risk disclosure for intermediate risk adults leads to reduction in MACE ahajournals.org/doi/10.1161/CI… Circulation: Genomic and Precision Medicine #ACC25 Small trial

Iftikhar J. Kullo (@iftikhar_kullo) 's Twitter Profile Photo

Admixture in humans is widespread & every individual is admixed to some degree A review by Yun Li et al of methods for local ancestry inference (LAI) & how LAI can be used for admixture mapping, association testing, and for calculating polygenic risk scores PRIMED Consortium

PRIMED Consortium (@prsdiversity) 's Twitter Profile Photo

Happy #DNADay25 from the PRIMED Consortium Consortium! Genetic information can help improve risk prediction for a broad range of health outcomes. Learn more: 🧬 Publications: primedconsortium.org/publications/p… 🧬 Research Highlights: primedconsortium.org/research/highl…