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The DREAM complex mediates gene repression during the G0 phase and coordinates gene expression in the G1/S and G2/M phases ebi.ac.uk/complexportal/… Search Complex Portal using GO:0070176 to see conservation across species #CotM

Want to learn how to navigate the UniProt website and use our powerful search tools? Register for our free webinar 21 September 2023, 15:30-16:30 BST). Discover how to use our tools (BLAST, Align, Peptide search, ID mapping) in the Tools results dashboard ebi.ac.uk/training/event…

We have now added the Rhea database reaction viewer to Complex Portal so you can learn more about our enzyme complexes. Take a look at the serine palmitoyltransferase complex, SPTLC1-SPTLC2-SPTSSA variant ebi.ac.uk/complexportal/…

The Rhea database viewer allows you to study the reaction catalyzed by this enzyme complex in more detail in the new Catalytic Activity section

You can take a look at the structure in the Complex Portal entry in a view provided by Protein Data Bank...

..and also see in which tissues the complex subunits are most heavily expressed thanks to Expression Atlas

Want to learn how to align UniProt variant data with results from Ensembl, Patrick Bell and #AlphaFold DB. Then register for our new, hands-on, virtual workshop Thursday 30th November 2023, 1pm-5pm (GMT) ebi.ac.uk/training/event…

Complex Portal release 245 out! 4431 biological complexes. ebi.ac.uk/complexportal/… (in sync with UniProt release 2023_04)

This family of LINC complexes mechanically couples cytoskeletal and nuclear components across the nuclear envelope, allowing the transmission of force. ebi.ac.uk/complexportal/… To find them all, search using GO:0034993 #CotM

IntAct release 245 is out! 1,284,582 binary interactions from 23,282 manually curated publications ebi.ac.uk/intact/about#s… (in sync with UniProt release 2023_04)

In collaboration with Complex Portal we have incorporated the Complex Viewer developed by Rappsilber laboratory into UniProt entries. Complexes curated by Complex Portal , UniProt, FlyBase S. pombe model organism knowledgebase SGD Project @[email protected] (bsky too) For example, see uniprot.org/uniprotkb/Q155…

Want to learn how to access the UniProt database using Python? Learn how to search for protein entries, filter data, run batch downloads and see examples of processing of downloaded data. Register for our free webinar 31 October 2024 15:00-16:00 (GMT) ebi.ac.uk/training/event…

Excited to share our preprint describing hu.MAP3.0. Here we integrate >25k mass spectrometry experiments to place ~75% of human proteins into 15k protein complexes. biorxiv.org/content/10.110…

Access the data at ebi.ac.uk/complexportal. So good to work with the groups of Kevin Drew and Georg Kustatscher on this.

at #HUPO2024 and want to learn more about how to use UniProt in your work. Visit our posters, Wednesday session. First how we support you in your proteomics research P-III-0816...

Hu.MAP3.0 released at #hupo2024, for details visit the posters on Wednesday. First learn about the data selection and machine learning algorithms P-III-0879...

Learn about capturing and representing a dynamic interactome at #hupo2024 P-III-0885...

🚧 Essential maintenance is planned to begin on Friday January 24th 2025. 🔧 The UniProt website may be temporarily unavailable. If this happens, please use our fallback wwwdev.ebi.ac.uk/uniprot/front-… during this time.

Find the true value of UniProt! A @PathOS EU-funded study by @CSIL finds @UniProt users save up to €5,475 & 219 hours/year. UniProt boosts research, biotech & healthcare by integrating 180+ databases with expert curation of publications. Read our Blog 👉 insideuniprot.blogspot.com/2025/06/unipro…

Want to learn more about macromolecular complexes? Register for our webinar on 𝗝𝘂𝗹𝘆 𝟵𝘁𝗵, 𝟮𝟬𝟮𝟱! Discover more about our latest updates including the Complex Navigator & the integration of ML-predicted complexes (huMap3.0 & MuSIC). ➡️ Register:tinyurl.com/bdy6wttv