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The scientific community is buzzing on Bluesky 🦋 You can now also follow us there: saezlab.bsky.social

Excited to report that we have discovered a new, endogenous molecular clock in unmodified human cells and tissues. It is ticking away right now in almost every cell in your body. Specifically, in a new paper on BioRxiv, we show that RNA editing by the near-ubiquitous ADAR1 in

How cute is this little guy? 😍

Nice to see our ScAPE ML model github.com/scapeML/scape as one of the best predictive models of this Kaggle challenge, now as part of the official baselines! Martín Garrido Rordríguez-Córdoba. Thanks to the organizers for this amazing competition.

We present NetworkCommons, a unified platform 🪐 for network biology, providing access to omics data, knowledge, and contextualization methods, all with a consistent API 👇 Paper: doi.org/10.1101/2024.1… Docs: networkcommons.readthedocs.io

Job opportunity! 🚨 Our lab, together with Muzlifah Haniffa's team at Wellcome Sanger Institute, is hiring an Advanced Research Assistant/Technical Specialist. We're looking for someone passionate about organoid modeling, CRISPR screening, and spatial technologies to help create accurate

We present Gene Regulatory nETwork Analsyis (GRETA), a framework to infer, compare and evaluate gene reg nets (GRN). With it, we have benchmarked multimodal and unimodal GRN inference methods. Check the results here 👇 Paper: doi.org/10.1101/2024.1… Code: github.com/saezlab/greta

Impressed to see how quickly the world is changing, how quickly we shape it through our ideas and research. Quoting from Marcos Matabuena's new blog: "Marcos, your ideas are very advanced, and sport will never be a mathematical science." (10-15 y ago) 👉digitalbiostatistics.com/2025/01/my-tho…

Did Metro Boomin use sound effects from the game "Street of Rage 2" in "Rap Saved Me" or am I crazy? youtu.be/LK9rgGmrH7I?t=… youtube.com/watch?v=GzsYST…

No AGI until LLMs can reliably produce useful LaTeX. Haven’t seen one that truly delivers. We need a LLM LaTeX benchmark!

I'm one of the young Europeans thinking about moving to the US/SF to find a stronger technical peer group. Thank you Musk, Trump and Bannon for making this such an easy decision in the last few weeks. I've never been more excited to build in general, but also to build

Diffusion language models are SO FAST!! A new startup, Inception Labs, has released Mercury Coder, "the first commercial-scale diffusion large language model" It's 5-10x faster than current gen LLMs, providing high-quality responses at low costs. And you can try it now!

I regret to inform you that all your goals are just shitty proxies for love and tribal belonging

Stephen Boyd's reaction when a student says they're using Genetic Algorithms for optimization is priceless 😂 youtube.com/watch?v=kV1ru-…

Reviewing BioML ICML papers feels like reading a lot of convoluted papers slapping on some ad hoc method from NLP to solve problems that don't actually exist... can someone convince me that this isn't the current state of the field 🥺

The latest version of Kasumi is now published in Nature Comms nature.com/articles/s4146… Kasumi identifies patterns in tissue patches enabling analysis of disease progression and treatment response while providing insights into spatial coordination at cell-type or marker level

Great work by Omer Ali Bayraktar , Oliver Stegle , and Moritz Mall ! Happy that our Ahmet Rifaioğlu contributed to this study by mapping CCC events between spatially co-localized TME and malignant cells using LIANA+ 🧠 github.com/saezlab/liana-…

New Anthropic Research: Project Vend. We had Claude run a small shop in our office lunchroom. Here’s how it went.

How can we find out what’s going on inside cells when we’re generating so much complex data? CORNETO is an open-source tool that uses machine learning to turn tangled omics datasets into clear maps of how genes, proteins and signalling pathways interact. ebi.ac.uk/about/news/res…

🎉 The revised version of CORNETO, our unified Python framework for knowledge-driven network inference from omics data, is published in peer reviewed form 🔗 Paper: nature.com/articles/s4225… 📖 News & Views: nature.com/articles/s4225… 💻 Code: corneto.org 🧵 Thread 👇