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Great to see the statistical analysis plan for the Ankle Arthritis RCT published! #transparency Looking forward to seeing the results! Total ankle replacement vs arthrodesis for end-stage ankle osteoarthritis 🦶 Patrick Muller Simon Skene rdcu.be/b1U1w

Published this week in Cancer Epidemiology 'Temporal and geographic changes in stage at diagnosis in England during 2008–2013: A population-based study of colorectal, lung and ovarian cancers'. Research by Inequalities in Cancer Outcomes Network's Patrick Muller Check it out here!: sciencedirect.com/science/articl…

SAP published for the KERALINK trial, testing the hypothesis that corneal cross-linking (CXL) treatment reduces the progression of keratoconus in comparison to standard care in patients aged 10–16 years. Results expected later this year! #keratoconus trialsjournal.biomedcentral.com/articles/10.11…

The BEAT-LUPUS trial analysis plan is now published! Will evaluate anti-dsDNA and flares, and whether effect of belimumab is mediated through steroid dose changes. Results later in 2020. Michael Ehrenstein Caroline Gordon UCL Comprehensive Clinical Trials Unit Versus Arthritis trialsjournal.biomedcentral.com/articles/10.11…

There are several reasons to think that the new UK #SARSCoV2 variant is an important one as it might be more contagious than other variants, but there are also some uncertainties. So much misinformation is being circulated, so this thread brings key data together. 🧵

Its taken 8 years to publication today! Thanks to the colleagues, funders and patients who made this possible. 3fold fewer #lupus flares with belimumab after Rituximab Versus Arthritis⁩ ⁦NIHR UCLH Biomedical Research Centre⁩ ⁦GSK⁩ ⁦UCL⁩ ⁦Lupus UK⁩ acpjournals.org/doi/10.7326/M2…

Now available fully open access in AJOG: our cohort study on how 10-year reoperation risk varies between women who had different initial surgical treatments for stress urinary incontinence. ajog.org/article/S0002-…

New paper in The Lancet using NMPA data estimates the proportion of adverse birth outcomes (stillbirth, preterm birth, and fetal growth restriction) in England that are attributable to socioeconomic & ethnic inequality. Read here: authors.elsevier.com/a/1e081V-4XDRsK RoyalCollegeObsGyn London School of Hygiene & Tropical Medicine

Stark racial and social inequalities in pregnancy outcomes in over a million births | LSHTM lshtm.ac.uk/newsevents/new… Jen Jardine Patrick Muller @JanvanderMeule6 Asma Khalil Kirstin Webster

Published today our sprint audit on Ethnic and Socio-economic Inequalities in Maternity and Perinatal Care. Read the report here: maternityaudit.org.uk/FilesUploaded/… RoyalCollegeObsGyn Healthcare Quality Improvement Partnership London School of Hygiene & Tropical Medicine Royal College of Midwives 💙 RCPCH

#COVID19 dogs could revolutionise how we detect the virus. But these clever canines need your help getting odour samples 🐕‍🦺 If you've taken a positive #PCR test in the past 3⃣ days, find out how you can volunteer 👉 bit.ly/32T9NSA Medical Detection Dogs Durham University

Ipek Gurol-Urganci & colleagues study obstetric intervention rates and pregnancy outcomes in England during the first year of the COVID-19 pandemic: doi.org/10.1371/journa… @profasmakhalil RoyalCollegeObsGyn @NMPA_audit CRR Patrick Muller Ipek Gurol Urganci Jen Jardine #pregnancy #COVID

It’s not about the money

Patrick Muller, Amar M Karia & colleagues investigate adverse outcomes in women with low-risk pregnancies undergoing induction of labour at 39 weeks, according to ethnicity, socioeconomic deprivation and parity: doi.org/10.1371/journa… Patrick Muller Kirstin Webster Ipek Gurol Urganci

Risk of premature birth up to 50% higher in mothers with poor mental health according to 🆕 research in @TheLancetPsych 🧠 ✍️ Ipek Gurol Urganci Patrick Muller @JanvanderMeule6 & colleagues King's College London RoyalCollegeObsGyn St George's, University of London (1752-2024) dmuleicester University of Liverpool University of Sydney 👉 bit.ly/3ODA9fK

AI vs Blueberry, a thread:

Delighted to lead the #CHAIhub with @GlockerBen (Imperial College London), Hana Chockler (King's College London), Sperrin (UniversityManchester ), Sabina Leonelli (University of Exeter), Ricardo Silva (UCL). We will bring together #academia and #industry for #causal #AI for #health real data 1/2