Pablo Jiménez (@pauljil) 's Twitter Profile
Pablo Jiménez

@pauljil

Medical Oncologist. MD MSc. Clinical Research Fellow. The Royal Marsden NHS Foundation Trust. Interested in HN&GU,Early phase Clinical Trials! Tweets my own.

ID: 303180415

calendar_today22-05-2011 12:42:30

247 Tweet

269 Followers

590 Following

Balazs Halmos (@balazshalmosmd) 's Twitter Profile Photo

Penpulimab approved for non-keratinizing NPC (follows recent approval of toripalimab for similar indication) Now i do not have much else to say about this besides the fact that as a Hungarian i MUST highlight that “puli” stands for the smartest/cutest magyar (Hungarian) dog

Michael Serzan, MD (@mikeserzanmd) 's Twitter Profile Photo

🗣️Prostate Oral Abstract #ASCO25 👉Abst5000: Dr #TedDeWeese presenting #CAN2409+prodrug +EBRT +/-ADT in Int/High Risk PCa #CAN2409 is a replication-defective adenovirus 🦠HSV-tk gene 🧬 w/ prodrug promoting immunogenic cell death ☠️ and immunize 💉against tumor antigens for

🗣️Prostate Oral Abstract #ASCO25

👉Abst5000: Dr #TedDeWeese
presenting #CAN2409+prodrug +EBRT +/-ADT in Int/High Risk PCa 

#CAN2409 is a replication-defective adenovirus 🦠HSV-tk gene 🧬 w/ prodrug promoting immunogenic cell death ☠️ and immunize 💉against tumor antigens for
TTCC-GrupoTratamiento Tumores Cabeza y Cuello (@ttccgroup) 's Twitter Profile Photo

NIVOPOSTOP Trial Demonstrates DFS Benefit of Adjuvant Nivolumab in High-Risk HNSCC Following Chemoradiotherapy dailynews.ascopubs.org/do/nivopostop-…

Pablo Jiménez (@pauljil) 's Twitter Profile Photo

After Keynote689, some questions/brain storming: 💢Benefit even for PDL1 CPS/TPS negative pts? Only 16 pts per arm 🩹OS and local relapse/PD% in future IAs 💡Level of impact from neoadj part? 🩻 Benefit stratification depending mPR/neoORR? 🖋️Description of ~12% cases not

After Keynote689, some questions/brain storming:
💢Benefit even for PDL1 CPS/TPS negative pts? Only 16 pts per arm
🩹OS and local relapse/PD% in future IAs
💡Level of impact from neoadj part? 
🩻 Benefit stratification depending mPR/neoORR?
🖋️Description of ~12% cases not
Dr Amol Akhade (@suyogcancer) 's Twitter Profile Photo

New Systematic Review (Cancer Cell, June 2025) 💉 Low-dose PD-(L)1 for Cancer Immunotherapy Largest Review till date 📊 32 studies | 2,055 pts ✅ >65% showed ≥80% cost savings 🧬 Responses seen in HL, lung, RCC 🏥 53% studies from LMICs 🧠 Bottom line: 💸 Promising for access.

New Systematic Review (Cancer Cell, June 2025)
💉 Low-dose PD-(L)1 for Cancer Immunotherapy
Largest Review till date 
📊 32 studies | 2,055 pts
✅ >65% showed ≥80% cost savings
🧬 Responses seen in HL, lung, RCC 
🏥 53% studies from LMICs
🧠 Bottom line:
💸 Promising for access.
Salivary Gland Cancer | Charity (@sgcanceruk) 's Twitter Profile Photo

Looking back on #ESMORareCancers25 💙 We proudly shared two UKSGCRWG-led studies on salivary gland cancer, highlighting the urgent need for research and collaboration in this rare disease space. #SGCUK #RareCancers #CancerResearch #Oncology

Looking back on #ESMORareCancers25 💙
We proudly shared two UKSGCRWG-led studies on salivary gland cancer, highlighting the urgent need for research and collaboration in this rare disease space.
#SGCUK #RareCancers #CancerResearch #Oncology
Pablo Jiménez (@pauljil) 's Twitter Profile Photo

Our new paper on low-dose anti-PD-(L)1 is now published in European Journal of Cancer! Incredible experience working alongside all the co-authors on such an important topic Dario Trapani Dr Amol Akhade Dr Amol Akhade 👇 doi.org/10.1016/j.ejca…

Dana-Farber News (@danafarbernews) 's Twitter Profile Photo

#BREAKING The FDA has approved pembrolizumab as the first new standard-of-care treatment for patients with resectable locally advanced #HeadandNeck cancer in 20+ years. Approval based on the pivotal KEYNOTE-689 trial led by Ravi Uppaluri, MDPhD of the Dana-Farber Brigham Cancer Center.

#BREAKING The <a href="/FDA/">FDA</a> has approved pembrolizumab as the first new standard-of-care treatment for patients with resectable locally advanced #HeadandNeck cancer in 20+ years. Approval based on the pivotal KEYNOTE-689 trial led by <a href="/DrUppaluri/">Ravi Uppaluri, MDPhD</a> of the <a href="/DanaFarber/">Dana-Farber</a> Brigham Cancer Center.
Pablo Jiménez (@pauljil) 's Twitter Profile Photo

💥Neoadjuvant pembrolizumab has received the approval for PDL1 CPS≥1 head&neck SCC by FDA! 🛎️This will require quick CPS testings Not surprising seen this restricion for negative CPS, having only 16 patients in each arm of KEYNOTE689 without presenting their specific outcomes

💥Neoadjuvant pembrolizumab has received the approval for PDL1 CPS≥1 head&amp;neck SCC by FDA! 

🛎️This will require quick CPS testings

Not surprising seen this restricion for negative CPS, having only 16 patients in each arm of KEYNOTE689 without presenting their specific outcomes
EL PAÍS (@el_pais) 's Twitter Profile Photo

Los científicos advierten de los riesgos en el procedimiento que se ha hecho Orlando Bloom recientemente y que no hay evidencia de que este sistema funcione, por lo que apelan a centrarse en la prevención: reducir al máximo la exposición a microplásticos elpais.com/salud-y-bienes…

Pablo Jiménez (@pauljil) 's Twitter Profile Photo

🚨Neo and adjuvant pembrolizumab for patients with resectable head and neck squamous cell carcinoma (KEYNOTE689) is now published in NEJM 💥Great step forward in the field Awaiting OS in next interim analyses Will NIVOPOSTOP be approved by FDA as well? U.S. FDA What would be

🚨Neo and adjuvant pembrolizumab for patients with resectable head and neck squamous cell carcinoma (KEYNOTE689) is now published in <a href="/NEJM/">NEJM</a>

💥Great step forward in the field
Awaiting OS in next interim analyses

Will NIVOPOSTOP be approved by FDA as well? <a href="/US_FDA/">U.S. FDA</a> 

What would be
Gabriel Puche, MD/PhD (@gabi_puchepalao) 's Twitter Profile Photo

🧵 ¿Apixabán🆚 rivaroxabán para ETEV? 📊 Nuevos datos comparativos sobre seguridad y eficacia. Lana Castellucci presentando el ensayo 🐍COBBRA - el 1er ECA que compara apixabán🆚 rivaroxabán durante 3 meses. Los resultados son claros… te lo cuento en este hilo 👇 #ISTH2025

Iván Márquez Rodas 🇪🇦 (@ivanpantic1980) 's Twitter Profile Photo

Happy to share the final results of the 🇪🇸 & 🇫🇷 ph2 trial of intratumoral BO-112 + pembro for patients with anti PD-1 resistant #melanoma. 25% ORR and 54% patients alive at 2 years. 16 years of basic and clinical research behind. Some context here 👇🧵 ascopubs.org/doi/10.1200/JC…

Noelia Tarazona (@tarazonanoelia) 's Twitter Profile Photo

🔥 We got the cover of the June issue of Nature Cancer with our paper! 🌟 A huge honor and a recognition of the team’s hard work. 🔗 lnkd.in/dd6dE7A4 📄 See lnkd.in/dfd3hfi2

🔥 We got the cover of the June issue of <a href="/NatureCancer/">Nature Cancer</a> with our paper! 🌟 A huge honor and a recognition of the team’s hard work.

🔗 lnkd.in/dd6dE7A4

📄 See lnkd.in/dfd3hfi2
Pablo Jiménez (@pauljil) 's Twitter Profile Photo

💥New combined updated long-term analysis from RTOG 9501 + EORTC 22931 published this week in Annals of Oncology ESMO - Eur. Oncology Median follow-up 7 years 💢Survival benefit from postop CRT may be not limited to patients with HNSCC positive margins or ENE (highlighted in figure) ⁉️Should

💥New combined updated long-term analysis from RTOG 9501 + EORTC 22931 published this week in <a href="/Annals_Oncology/">Annals of Oncology</a> <a href="/myESMO/">ESMO - Eur. Oncology</a> 
Median follow-up 7 years
💢Survival benefit from postop CRT may be not limited to patients with HNSCC positive margins or ENE (highlighted in figure)
⁉️Should
LARVOL (@larvol) 's Twitter Profile Photo

For Head and Neck Cancer Day, we’re highlighting the top #HNC oncologists with most views on 𝕏 in 2025. 🔗 Follow us for latest clinical trials and insights from the world of oncology 👉 clin.larvol.com #LARVOL #CancerResearch #Oncology #ClinicalTrials #CancerData

For Head and Neck Cancer Day, we’re highlighting the top #HNC oncologists with most views on 𝕏 in 2025.

🔗 Follow us for latest clinical trials and insights from the world of oncology 👉 clin.larvol.com 

#LARVOL #CancerResearch #Oncology #ClinicalTrials #CancerData
LARVOL (@larvol) 's Twitter Profile Photo

On Head and Neck Cancer Day, we’re sharing key anticipated milestones expected in 2025. 🔗 Follow us for latest clinical trials and insights from the world of oncology 👉 clin.larvol.com #LARVOL #CancerResearch #Oncology #ClinicalTrials #CancerData #OncologyInsights

On Head and Neck Cancer Day, we’re sharing key anticipated milestones expected in 2025.

🔗 Follow us for latest clinical trials and insights from the world of oncology 👉 clin.larvol.com

#LARVOL #CancerResearch #Oncology #ClinicalTrials #CancerData #OncologyInsights