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PRC Highlight: The @circle_J_Labs is making strides in understanding diseases at the molecular level — paving the way for #future breakthroughs in #oral health and beyond NYU Dentistry New York University #Jensenlab #3minutemondays buff.ly/Xa07Q5I

Detailed characterization of VGSCs (Nav1.7, 1.8, 1.9) in pain-sensing neurons. Reveals new insights into their roles in action potential generation and pain disorders #painresearch #ionchannels buff.ly/UZ8JmY8

Our paper in PAIN Journal “Small molecule targeting NaV1.7 via inhibition of CRMP2-Ubc9 interaction reduces pain-related outcomes in a rodent osteoarthritic model”, was featured in the April 2025 Science, Medicine, and the Anesthesiologist (SM&A) of Anesthesiology.

New paper from the lab - Functional characterization of a novel de novo #CACNA1C pathogenic variant in a patient with neurodevelopmental disorder #calcium #ionchannels #channelopathies Charles University ➡️ rb.gy/9teu05

New paper in collaboration between Centre of Biosciences SAS & Charles University - Electrophysiological characterization of sourced human iPSC-derived motor neurons #ionchannels #mnd #als ➡️ rb.gy/5tdf7r

G proteins inhibit CaV2.2 by selectively blocking VSDs I & IV, revealing the mechanism of presynaptic inhibition #ionchannels #CaV22 #Gproteins #neuroscience science.org/doi/10.1126/sc…

NaV1.8/NaV1.9 double knockout mice show their combined role in pain signaling & altered gene expression in DRG neurons. Valuable for studying human pain mutations #ionchannels #pain #neuroscience buff.ly/WPmALVF

Alpha-bisabolol & camphene, known for pain relief, also show promise against itch! They reduce histamine-induced scratching in mice via Cav3.2 channels #ionchannels #itch #neuroscience molecularbrain.biomedcentral.com/articles/10.11…

CaV1.3 channels are vital for dopamine neuron function. We found that mutant LRRK2 (G2019S) enhances their activity via CaVβ3 phosphorylation, a potential key factor in Parkinson's disease. #neuroscience #ionchannels #ParkinsonsDisease #LRRK2 #CaV1.3 mdpi.com/1422-0067/26/7…

📢 New paper from the lab of Dr. Jie Yu of Zhejiang Chinese Medical University. Great work Jie and team 🥳 #CRMP2 #TCells #ImmuneConnection #ArthriticPain CRMP2 phosphorylation regulates polarization and spinal... : PAIN journals.lww.com/pain/fulltext/…

Kicked off the USASP meeting last night with a mega pretzel at the NYU Pain Research Center dinner. Great start to a great week! #USASP2025 #PainResearch #NYUPRC #NetworkingAndPretzels

Congrats to all the poster award winners at #usasp2025!! Very proud of my good friend Paz Duran who won an award for her work in basic science! Amazing work all around! 🙌😎

Had an amazing time at the #USASP2025 meeting! I am grateful to be part of such an inspiring and supportive community. Looking forward to what’s next! #painresearch #neuroscience #USASP

PRC Highlight: Congrats to Paz Duran de Haro for "Best Poster Presentation Finalist in Basic Science" Titled "Compartmentalized Signaling Of Mas-related G-protein Coupled Receptor X1 (MrGPRX1) And Transient Receptor Potential Vanilloid (TRPV) Channels In Pain And Itch Pathways"👏

Surgeries are a common source of #pain in the clinic. Check out our new paper published today in PNAS exploring how stress can lead to enhanced pain after surgery. We found that targeting prolactin can improve outcomes in females. PNASNews. pnas.org/doi/10.1073/pn…

Jason J. McDougall et al. find that visual exposure to green light reduced joint pain in osteoarthritic rats independent of nociceptor activity. Analgesic endolipids were upregulated, suggesting involvement of the endocannabinoid system. Learn more in #PAIN bit.ly/3S2xpe3

What do you think this finding from Harrison Stratton, PhD and @PNAS News may mean for the future of postoperative pain management in women? bit.ly/43qQVpQ #PRF #endometriosis

Excited to share my first senior author paper in Pain! 🎉 We identify Synj1 & EndoA1 as key endocytic mediators of nociception. Silencing them blocks spinal synaptic transmission and relieves pain in cancer & postoperative models. buff.ly/caKMGY3

🔊New pre-print from the lab, led entirely by the inimitable & brilliant Tyler Nelson and a new collab with Michael Gold Mouse models of non-dystrophic and dystrophic myotonia exhibit nociplastic pain-like behaviors biorxiv.org/content/10.110…

Come join us in the Peach Lab! New job opening for a Research Assistant at Centre Of Membrane Proteins and REceptors. Applications welcome until 22nd July jobs.nottingham.ac.uk/vacancy.aspx?r…