Peiwen Chen (@peiwenchen9) 's Twitter Profile
Peiwen Chen

@peiwenchen9

Cancer research lab focusing on symbiotic interactions between tumor cells and immune cells (macrophages, microglia, MDSCs and T cells). Views are my own.

ID: 1239725060124000261

calendar_today17-03-2020 01:27:51

91 Tweet

145 Followers

131 Following

Peiwen Chen (@peiwenchen9) 's Twitter Profile Photo

Our new paper “Hypoxia-driven protease legumain promotes immunosuppression in glioblastoma” is out in Cell Reports Medicine. This is a team effort and includes three co-first authors Lizhi, Songlin and Fatima. Thanks so much for reviewers and editor. cell.com/action/showPdf…

Peiwen Chen (@peiwenchen9) 's Twitter Profile Photo

Our manuscript focusing on LDHA-regulated tumor-macrophage symbiosis in glioblastoma is finally out Nature Communications. nature.com/articles/s4146… Thanks all editors and reviewers.

Peiwen Chen (@peiwenchen9) 's Twitter Profile Photo

Please check our review regarding epigenetic-regulated tumor-immune interactions in glioma. Thanks to all authors, reviewers and the editor from Trends in Molecular Medicine

Lurie Cancer Center (@luriecancer) 's Twitter Profile Photo

Findings from Lurie Cancer Center's Peiwen Chen and collaborators suggest that a metabolism-related gene, LDHA, could serve as a potential therapeutic target for #glioblastoma, according to a recent study in Nature Communications. news.feinberg.northwestern.edu/2024/03/26/inv… via Northwestern Feinberg School of Medicine #BTSM

Peiwen Chen (@peiwenchen9) 's Twitter Profile Photo

Thanks Trends in Molecular Medicine and the editor Dr. Aliki Perdikari for highlighting our review regarding epigenetic-regulated tumor-immune symbiosis in glioma on the May issue cover! cell.com/trends/molecul…

Thanks <a href="/TrendsMolecMed/">Trends in Molecular Medicine</a> and the editor Dr. Aliki Perdikari for highlighting our review regarding epigenetic-regulated tumor-immune symbiosis in glioma on the May issue cover!  cell.com/trends/molecul…
Peiwen Chen (@peiwenchen9) 's Twitter Profile Photo

Thanks Cancer Research for this opportunity to write the commentary highlighting a fantastic paper from Cell “Macrophage-mediated myelin recycling fuels brain cancer malignancy” by Dr. Leila Akkari and colleagues. aacrjournals.org/cancerres/arti…

Peiwen Chen (@peiwenchen9) 's Twitter Profile Photo

Excited to share our paper just accepted by Journal of Clinical Investigation. We reveal a new macrophage-microglia interplay in GBM and develop a powerful therapeutic approach targeting them. jci.org/articles/view/…

Cancer Research (@cr_aacr) 's Twitter Profile Photo

Lipid-laden #macrophages recycle #myelin to feed #glioblastoma—this In the Spotlight commentary by Peiwen Chen and colleagues highlights a recent Cell paper by Leila Akkari et al. bit.ly/3zNHPZs

Lipid-laden #macrophages recycle #myelin to feed #glioblastoma—this In the Spotlight commentary by <a href="/PeiwenChen9/">Peiwen Chen</a> and colleagues highlights a recent <a href="/CellCellPress/">Cell</a> paper by <a href="/LeilaAkkari1/">Leila Akkari</a> et al. 
bit.ly/3zNHPZs
Peiwen Chen (@peiwenchen9) 's Twitter Profile Photo

Excited to share our review: “Immunotherapy for GBM: current state, challenges, and future perspectives ", just published in @Cellular & Molecular Immunology rdcu.be/dW19V

Cancer Research (@cr_aacr) 's Twitter Profile Photo

Read the In The Spotlight commentary "Lipid-laden macrophages recycle myelin to feed glioblastoma:" bit.ly/3Ogkovn By Peiwen Chen and colleagues discussing a recent Cell paper by @LeileAkkari1 et al.

Read the In The Spotlight commentary "Lipid-laden macrophages recycle myelin to feed glioblastoma:" bit.ly/3Ogkovn

By <a href="/PeiwenChen9/">Peiwen Chen</a> and colleagues discussing a recent <a href="/CellCellPress/">Cell</a> paper by @LeileAkkari1 et al.
Peiwen Chen (@peiwenchen9) 's Twitter Profile Photo

Check out our review article: Protease Regulation of Tumor-Immune Cell Symbiosis, just online Trends in Cancer, huge thanks the editor for this opportunity. kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…

Peiwen Chen (@peiwenchen9) 's Twitter Profile Photo

Happy to share our work out at Journal of Clinical Investigation We identified a new tumor-macrophage interaction contributing to GBM progression/immunosuppression and found that targeting the symbiosis sensitizes GBM to immunotherapy. Huge thanks to editors and reviewers. jci.org/articles/view/…

Journal of Clinical Investigation (@jclinicalinvest) 's Twitter Profile Photo

Improving immunotherapy in glioblastoma! Peiwen Chen & team Cleveland Clinic discover targeting legumain—which promotes infiltration of tumor-associated macrophages via the GSK3β/STAT3 pathway—has anti-tumor effects and improves immunotherapy in preclinical GBM models:

Peiwen Chen (@peiwenchen9) 's Twitter Profile Photo

Our work focusing GPNMB -mediated GSC-TAM symbiosis is out JCI insight insight.jci.org/articles/view/… Thanks to all authors, editors and reviewers.

JCI insight (@jci_insight) 's Twitter Profile Photo

Disrupting cell communication in glioblastoma— Peiwen Chen and team Cleveland Clinic discover GPNMB mediates bidirectional communication between GBM stem cells and tumor-associated macrophages and microglia: insight.jci.org/articles/view/…

Disrupting cell communication in glioblastoma—

<a href="/PeiwenChen9/">Peiwen Chen</a> and team <a href="/ClevelandClinic/">Cleveland Clinic</a> discover GPNMB mediates bidirectional communication between GBM stem cells and tumor-associated macrophages and microglia: insight.jci.org/articles/view/…
Peiwen Chen (@peiwenchen9) 's Twitter Profile Photo

Grateful and honored to receive the CLIP award from Cancer Research Institute . This support will enable us to investigate the biology of MDSCs, and to develop novel immunotherapies targeting these cells in glioblastoma. Thank you to CRI for supporting our work—excited for what’s ahead!