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We’re thrilled to announce that Sean Hennessy, PharmD, PhD, (Sean Hennessy) received the William B. Abrams Award in Geriatric Clinical Pharmacology award at the ASCPT Journal Family 2024 Annual Meeting. Join us in celebrating his remarkable achievements in Pharmacology.

Check out the latest in Pharmacoepidemiology & Drug Safety, featuring several CREST investigators ⬇️ Adherence with statins and all-cause mortality in days with high temperature Todd Miano, PharmD,PhD Sean Hennessy Dept. of Biostatistics, Epidemiology & Informatics onlinelibrary.wiley.com/doi/10.1002/pd…

Newly published in Hepatology and led by CREST investigator Dr. Tess Bittermann: Real-world evidence for factors associated with maintenance treatment practices among U.S. adults with autoimmune hepatitis Dept. of Biostatistics, Epidemiology & Informatics journals.lww.com/hep/abstract/9…

Check out the latest in JAMA Internal Medicine featuring several CREST investigators ⬇️ Severe Acute Liver Injury After Hepatotoxic Medication Initiation in Real-World Data Sean Hennessy Dept. of Biostatistics, Epidemiology & Informatics jamanetwork.com/journals/jamai…

Newly published in JAMA Neuro. and led by our own Emily Acton ⬇️ Direct-Acting Oral Anticoagulants and Antiseizure Medications for Atrial Fibrillation and Epilepsy and Risk of Thromboembolic Events Sean Hennessy Charles E Leonard Dept. of Biostatistics, Epidemiology & Informatics jamanetwork.com/journals/jaman…

New in the American Journal of Epidemiology and led by our talented former post doc Hanxi (Molly) Zhang) ⬇️ Grace periods and exposure misclassification in self-controlled case-series studies of drug-drug interactions Charles E Leonard Sean Hennessy Todd Miano, PharmD,PhD academic.oup.com/aje/advance-ar…

A great first day of sessions at #ISPEAnnual2024 in beautiful Berlin!

Check out the latest from the CREST team in Clinical Pharmacology & Therapeutics ⬇️ Concomitant Use of Oral Anticoagulants with Oral Dipeptidyl Peptidase-4 Inhibitors and Serious Bleeding Events Phương P Sean Hennessy Charles E Leonard Todd Miano, PharmD,PhD ascpt.onlinelibrary.wiley.com/doi/10.1002/cp…

Newly published in Clinical Pharmacology & Therapeutics ⬇️ Risk of Opioid Overdose Associated with Concomitant Use of Methadone and Statins Cheng Chen Todd Miano, PharmD,PhD Charles E Leonard Sean Hennessy ascpt.onlinelibrary.wiley.com/doi/10.1002/cp…

Spotlighting an excellent paper by one of our first-year PhD students, Lin-Chieh Meng! Paternal metformin use and risk of congenital malformations in offspring in Norway and Taiwan: population based, cross national cohort study Lin-Chieh Meng bmj.com/content/387/bm…

Check out the latest in JAMA Network Open, led by CREST investigator Mark Neuman ⬇️ Strategies to Limit Benzodiazepine Use in Anesthesia for Older Adults: A Randomized Clinical Trial Mark Neuman jamanetwork.com/journals/jaman…

Interested in joining the CREST team? We're hiring! ⬇️ Manager Research Project B (Department of Biostatistics, Epidemiology and Informatics) wd1.myworkdaysite.com/recruiting/upe…

Ambient temperature & serious adverse health outcomes among users of different antidiabetes drugs ft. Charles E Leonard, Kacie Bogar, Colleen Brensinger, Warren Bilker, Cheng Chen & Sean Hennessy Penn CREST UPenn CCEB Dept. of Biostatistics, Epidemiology & Informatics PennSysPharmATT bmjopen.bmj.com/content/14/10/…

Newly published in Clinical Pharmacology and Therapeutics and featuring several CREST investigators: Risk of Hypoglycemia Associated with Concomitant Use of Insulin Secretagogues and ACE Inhibitors in Adults with Type 2 Diabetes: A Systematic Review ascpt.onlinelibrary.wiley.com/doi/10.1002/cp…

A great methods paper featuring several CREST investigators, newly published in the Electronic Journal of Statistics: Structural mean models for instrumented difference-in-differences Tat-Thang Vo Sean Hennessy Dept. of Biostatistics, Epidemiology & Informatics projecteuclid.org/journals/elect…

New publication in Journal of Geriatric Psychiatry and Neurology led by Phương P and featuring several CREST investigators ⬇️ Impact of Anticholinergic Burden and Clinical-Demographic Characteristics on Incident Dementia in Parkinson Disease journals.sagepub.com/doi/full/10.11…

Check out the latest from the CREST team in Pharmacoepidemiology & Drug Safety: Evaluation of Drug–Drug Interactions in Pharmacoepidemiologic Research Cheng Chen Phương P Todd Miano, PharmD,PhD Charles E Leonard Sean Hennessy onlinelibrary.wiley.com/doi/10.1002/pd…

Great new paper in Clinical Pharmacology & Therapeutics led by doctoral student Haedi Thelen: Characterizing Treatment Effect Heterogeneity Using Real-World Data ascpt.onlinelibrary.wiley.com/doi/10.1002/cp… Haedi Thelen Sean Hennessy

New in Pharmacoepidemiology & Drug Safety ⬇️ Real-World Data and Real-World Evidence in Regulatory Decision Making: Report Summary From the Council for International Organizations of Medical Sciences (CIOMS) Working Group XIII Sean Hennessy Dept. of Biostatistics, Epidemiology & Informatics onlinelibrary.wiley.com/doi/10.1002/pd…

New in American Journal of Epidemiology: Effect of exogenous testosterone on cardiovascular, cerebrovascular, and thromboembolic adverse events: Results of three complementary research designs Tat-Thang Vo Phương P Sean Hennessy Charles E Leonard academic.oup.com/aje/advance-ar…