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It’s impressive that self-awareness can be convincingly mimicked by a statistical language model. GPT

Third time’s a charm. GPT

ChatGPT is incredibly limited, but good enough at some things to create a misleading impression of greatness. it's a mistake to be relying on it for anything important right now. it’s a preview of progress; we have lots of work to do on robustness and truthfulness.

Alyssa, a 13-year old T-cell leukemia (ALL) patient in the UK, was the first person to receive a base editing therapeutic—T cells with three base edits—and the first patient reported to benefit from base editing: complete remission, 6 months later. 1/3 bbc.com/news/health-63…

The many surprises of the COVID-19 pandemic — the virus’ fast evolution, the many types of vaccines that worked, the erosion of trust in science, the collective forgetfulness,… statnews.com/2022/12/27/cov…

“Where 2022 excelled particularly was in technological strides.” nytimes.com/2022/12/31/opi…

Rob Toews Greg Brockman The importance of language in thought and reasoning is a persistent illusion. The main reason LLMs make factual, logical,and physical reasoning mistakes is that language is their only source of knowledge. The other main reason is that they have very limited reasoning abilities...

It's clear that we're far from peak LLM performance -- these models will keep getting better. It's also clear that pure generation is just the first step -- we can largely alleviate the LLM reliability issue by using them as information retrieval devices over a knowledge corpus.

Wow.

My recent tweets about anthropomorphism in #AI have got some attention, so I thought I should follow up with more explanation. Here's a🧵. 1/10

My take of ChatGPT and their ilk is a wee bit bullish.

Another day, another opinion essay about ChatGPT in the The New York Times. This time, Noam Chomsky and colleagues weigh in on the shortcomings of language models. Unfortunately, this is not the nuanced discussion one could have hoped for. 🧵 1/ nytimes.com/2023/03/08/opi…

“By what process the learning machine stores its knowledge, distills it and retrieves it remains […] unknown. […] the mystery associated with machine learning will challenge human cognition for the indefinite future.” apple.news/As0nCWyB5RQujE…

Reinforcement Learning by Human Feedback is just parenting for a supernaturally precocious child.

The route of the ENDURANCELIFE Sussex trail ultramarathon is spectacular. I recommend it, even as a long trail walk. I’ve had a great time this morning running up and down.

1/The call for a 6 month moratorium on making AI progress beyond GPT-4 is a terrible idea. I'm seeing many new applications in education, healthcare, food, ... that'll help many people. Improving GPT-4 will help. Lets balance the huge value AI is creating vs. realistic risks.

GPT-4-32K makes regular GPT-4 look like a toy. Here are some of the things it can do:

Our event exploring recent clinical and research developments of #NucleicAcid medicines is now open! Get your tix and submit abstracts at conferences.nature.com/CrackingCode In partnership with Moderna Alnylam Pharmaceuticals WPI UMass Chan Medical School nature Nature Biomedical Engineering Nature Biotechnology Nature Immunology Nature Reviews Drug Discovery

I look forward to participating in the Keystone conferences Precision Genome Engineering and Delivery of Nucleic Acid Therapeutics. #KSGenomeEng24 #KSNADelivery24 hubs.la/Q026Mdwl0 hubs.la/Q026Md720

I’m recruiting two editors for our close-knit multidisciplinary team. The role involves constant learning, and offers flexibility in self-management and a sensible balance of independence and collaborative teamwork. careers.springernature.com/job-invite/496…