🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

#singlecell epigenomic technologies are redefining our understanding of cancer evolution. Now, Marthe LAISNE, Mathieu Lupien & Céline Vallot explain how epigenomic heterogeneity drives tumor cell state diversity through reprogramming and selection. go.nature.com/3NyflWN

Updated manuscript! We analyzed Cas9-generated indels at >2,800 synthetic Cas9 targets in 18 DNA repair deficient stem cell lines to learn about sequence-specific DNA repair. #GeneEditing #Cas9 #DNArepair Soon to be out! biorxiv.org/content/10.110…

Excited to share this collaborative effort with Dian Yang & Matt Jones, combining Cas9 evolving lineage tracing and spatial techniques to study lung cancer evolution. Great supports from Fei Chen Lab, Jonathan Weissman's Lab & Yosef Lab. biorxiv.org/content/10.110…

I haven’t posted much since Twitter is X, but I have a good reason today☺️ if you like #cancerstemcells #stemcells and #immunotherapy, this is for you! With partner in crime Phoenix Miao😎 nature.com/articles/s4156…

🚨 Great alternatives to BioRender are now available!! 📢 NIAID News offers a collection of public figures and icons for everyone to use. Check it out at bioart.niaid.nih.gov

Free scientific illustrations for biologists! 😍 NIH has released a library of 500+ free scientific illustrations to create figures, presentations, and illustrations! all freely available in the public domain. Retweet and spread the message! bioart.niaid.nih.gov

Job alert: Interested in pancreatic beta cells, a dash of genomics and novel treatment options for diabetes? We are looking for a post-doc!! Contact us for an informal chat! edzz.fa.em3.oraclecloud.com/hcmUI/Candidat…

PhD position available! We have a position available as part of the MIBTP programme (warwick.ac.uk/fac/cross_fac/…)on epigenetic regulation of stem cell fate in collaboration with the Cowley lab University of Leicester. Deadline for applications - 16th January 2025 Please share!

I have two PhD projects listed on this scheme - please get in touch if you are interested!

PhD position(s) in #development #genomics:  tinyurl.com/9dk9m29d European (#MSCA) doctoral training network,  #DanioreCODE (tinyurl.com/2rz4mdsa). How does  #transcription initiation regulation control #brain injury response and  #regeneration in #zebrafish?

Check out this new iSAM-Cas9 hESC line developed in the lab in colaboration with Antonella Fidanza and Ana Sevilla at Universitat de Barcelona! Nice tool to multiplex gente activation. frontiersin.org/journals/cell-…

In 2025 the University will celebrate its 125th anniversary. One of the ways it’s celebrating is by making a major investment in the Birmingham research community with the appointment of 125 Anniversary Fellows and Chairs. Uni of Birmingham Find out more: fellowsandchairs.birmingham.ac.uk

This week in The EMBO Journal! 👀 The authors reveal that early embryos undergo the transition from #totipotency to pluripotency by employing a relay between histone methyltransferases MLL2 and SETD1A/B to deposit H3K4me3. 📚 Give it a read: bit.ly/4gonk5e

Delighted to announce that our paper showing that PRMT5 drives chemo resistance in breast cancer stem cells by regulating splicing of DDR genes is published!! Big shout out to Kelly and Matthew. Funded by ⁦Cancer Research UK⁩, ⁦Breast Cancer Now⁩ search.app/Z4ZwpAfpfUojFX…

PRMT5 regulates chemoresistance in #BreastCancer stem cells by controlling the splicing of DNA damage response genes. Combining PRMT5 inhibitors with DNA damaging chemo kills BCSCs. New approaches to target drug resistant BCSCs from Davies Lab - CH3 🔎nature.com/articles/s4138…

Great to see such fantastic scientists (and people!) recognised by ISEH. Well done to all!

Very excited to share our new preprint about FLASH radiation and ferroptosis, now available on bioRxiv!

**NEW Doctoral Training Programme just launched!!** This exciting programme on Microbial Genomics for Health Protection is joint between IMIBirmingham Uni of Birmingham and UKHSA UK Health Security Agency 9 brilliant projects available!! birmingham.ac.uk/research/centr…