🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

It can be hard to fit mechanistic models to single cell data while accounting for the various types of noise (e.g., intrinsic, technical). Are some noise sources necessary to model, and others not? How can we fit models efficiently? Our new paper in Cell Systems addresses this!

Proud and inspiring moment to see indigenous Wixárika art (an ancient culture still thriving that has been an important personal inspiration for me) on the cover of nature featuring our Mexican Biobank study go.nature.com/46IxjxS Congrats Mauricio Guzman for a beautiful design!

Pervasive relaxed selection on spermatogenesis genes coincident with the evolution of polygyny in gorillas biorxiv.org/cgi/content/sh… #biorxiv_evobio

PhylteR, our new tool for filtering phylogenomics datasets, is now out! doi.org/10.1093/molbev… PhylteR identifies with precision, from a collection of gene trees, the "outlier" sequences responsible for a lack of concordance among gene trees. How it works? A small thread 👇

Glad to announce that the last update of OrthoMaM (v12) is now available and published in NAR! It now includes 15,868 high quality alignments of orthologous coding sequences (CDS) for up to 190 mammals! Check out the article for more information: doi.org/10.1093/nar/gk…

The evolution of GC-biased gene conversion by means of natural selection biorxiv.org/cgi/content/sh… #biorxiv_evobio

Distribution theories for genetic line of least resistance and evolvability measures: Junya Watanabe ow.ly/uNea50T8uUu

This paper from Thomas Hansen argues that distinct modes of evolution at different time scales act to decouple micro- and macroevolution: academic.oup.com/jeb/advance-ar…

1/ A thread about mutation and recombination in vertebrates and what we learned by studying three-generation pedigrees of zebra finches. Take home: the remarkable similarities between birds and mammals in many properties of these fundamental processes.