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Should children be vaccinated against COVID-19? adc.bmj.com/content/early/… #COVID19 #children #vaccines #MCRI #paediatrics ADC Petra Zimmermann Laure Pittet Adam Finn Andrew Pollard Nigel Curtis

Samuel Arthur Rhedin ESPIDSociety This important work is now finally published and can be found here: journalofinfection.com/article/S0163-… Nigel Curtis Laure Pittet Quynh Duong

Hepatitis B vaccine co-administration influences the heterologous effects of neonatal BCG vaccination in a sex-differential manner sciencedirect.com/science/articl… Laure Pittet DrNic @GermanoSusie Murdoch Children's Research Institute (MCRI)

The Challenge of Studying Long COVID: An Updated Review (Feb 2022) bit.ly/3hr4Uo2 Petra Zimmermann Laure Pittet Ped Infect Diseases Murdoch Children's Research Institute (MCRI) The Royal Children's Hospital, Melbourne UniMelb MDHS University of Melbourne ESPIDSociety Infectious Diseases PIDS ASIDANZ Team DFTB

What is the significance of an accelerated BCG reaction in children? adc.bmj.com/content/early/… Induration/swelling at #BCG injection site within 72h warrants investigation for #TB Paola Laure Pittet ADC ESPIDSociety Infectious Diseases PIDS ASIDANZ Team DFTB

BCG vaccination alters immune responses to #SARSCoV2 in the test tube. We need to await imminent results from the #BRACEtrial RCT to find out whether this translates into clinical protection. Led by DrNic Murdoch Children's Research Institute (MCRI) The Royal Children's Hospital, Melbourne UniMelb MDHS onlinelibrary.wiley.com/doi/10.1002/ct…

#IDTwitter ❌Long IV 💉courses for 👶young infants with UTI ❌ Early oral switch <7d ✅for most, including with bacteraemia. @GweeAmanda Rod Hunt Laure Pittet Dr Eloise Silvester et al. Murdoch Children's Research Institute (MCRI) ADC adc.bmj.com/content/early/…

Review of >23’300 screened studies summarising the effect of early-life antibiotic exposure on children‘s health. Significantly increased risk for several diseases, incl eczema, allergies, asthma and obesity Quynh Duong Laure Pittet Nigel Curtis ESPIDSociety Murdoch Children's Research Institute (MCRI)

journalofinfection.com/article/S0163-…

Our latest MIS BAIR publication in BMJ Paeds Open! Sociodemographic, obstetric & neonatal factors + outcomes of a paediatric advice line associated w BCG vaccine RCT 💉 Nigel Curtis Laure Pittet doi.org/10.1136/bmjpo-…

We found an association between the bacterial composition of the intestinal microbiome at one week of age and the presence of eczema at 12 months. Mis Bair Nigel Curtis Laure Pittet Ömer Faruk Çetiner Murdoch Children's Research Institute (MCRI) Uni Fribourg frontiersin.org/articles/10.33…

Factors influencing scar formation following #BCG vaccination. sciencedirect.com/science/articl… #BRACEtrial Paola Laure Pittet DrNic Julio Croda, MD, PhD @adilia_warris Bruno Jardim Cristina Prat Aymerich Murdoch Children's Research Institute (MCRI) UniMelb MDHS The Royal Children's Hospital, Melbourne

Our review explores potential reasons for the inconsistent findings between the 11 trials that have reported the effect of #BCG vaccination on protection against symptomatic #COVID19. bit.ly/44wYhq6 Christie Noble @immunity_lab Laure Pittet Clinical Infectious Diseases #BRACEtrial #IDtwitter

BCG vaccine’s off-target effect on herpes simplex virus. Results from the international 🇦🇺🇳🇱🇬🇧🇪🇸🇧🇷 #BRACEtrial published today show a beneficial effect of BCG on cold sore recurrence. sciencedirect.com/science/articl… #BCG #vaccine #RCT #HSV #IDTwitter #WeAreID eClinicalMedicine – The Lancet Discovery Science

New RCT: #BCG #vaccination for protection against recurrent herpes labialis BCG-Denmark vaccination had a beneficial effect on herpes labialis, but may increase the risk of a first cold sore bit.ly/3RvuF9H @GweeAmanda Cristina Prat Aymerich

BCG given in the first few days of life has little effect on the composition of the intestinal microbiome at one week of age but does influence the abundance of certain metabolic pathways Nigel Curtis Laure Pittet Murdoch Children's Research Institute (MCRI) ESPIDSociety Ped Infect Diseases journals.lww.com/pidj/abstract/…

Inappropriate prescribing contributes to high antibiotic exposure in young children in Australia: bit.ly/3U3X2vA "At least two-thirds of children were prescribed antibiotics in the first 2y of life, and more than a quarter of these exposures may have been unnecessary."

Latest results from the international 🇦🇺🇳🇱🇬🇧🇪🇸🇧🇷 #BRACEtrial in ~6828 healthcare workers. In this RCT, BCG led to a small increased risk of febrile or respiratory illness in the 12m following (re)vaccination. bit.ly/4alRvGA

BCG vaccination to prevent febrile and respiratory illness in adults: secondary outcomes of a phase 3 RCT A small increased risk of symptomatic febrile or respiratory illness was observed in the 12 months following BCG vaccination in adults thelancet.com/journals/eclin…

The final January Editor's Choice article is "Long-term persistence of seroprotection against measles following measles-mumps-rubella vaccination administered before and after pediatric liver transplantation" by Pittet et al. buff.ly/3W8pUVm #pediatrics #vaccine