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Hi #MedTwitter #NurseTwitter: we're hearing from regulators that the "pandemic is over" and that clinicians are no longer reusing #PPE Not your experience? Please weigh in below!

The latest from Greater Boston Pandemic Fabrication Team is now up on medRxiv!

NEW from Greater Boston Pandemic Fabrication Team Harvard-MIT Center for Regulatory Science: 3D-Printed frames to enable reuse and improve the fit of #N95 and #KN95 respirators bmcbiomedeng.biomedcentral.com/articles/10.11…

Assessing the filtration efficiency and regulatory status of N95s and nontraditional filtering face-piece respirators available during the COVID-19 pandemic bmcinfectdis.biomedcentral.com/articles/10.11… via Greater Boston Pandemic Fabrication Team BMC

Great to see this joint work with Javier Ganz on the rates and patterns of somatic mutations in the normal human brain and early origin and evolution of brain tumors out on Cancer Discovery !

The PhD application assistance program for HMS_SysBio is back up and running for the 2021 admissions cycle! Please share with any undergrads/students planning on applying! docs.google.com/forms/d/e/1FAI…

Our paper on organelles in aging and age-related trait heritability has been posted to eLife - the journal (pre-proofing)!! Check out this great thread from Veera Rajagopal  on it. Looking forward to seeing the full version up online soon elifesciences.org/articles/68610

De Novo Powered Air-Purifying Respirator Design and Fabrication for Pandemic Response frontiersin.org/article/10.338… via Frontiers Greater Boston Pandemic Fabrication Team Harvard-MIT Center for Regulatory Science @HiTSatHarvard HST The Harvard/MIT MD-PhD Program Johns Hopkins Medicine Massachusetts Institute of Technology (MIT) MIT AeroAstro #PAPR

Excited to share VeloViz, my first PhD work in the JEFworks lab! We asked if using information on cells’ future transcriptional states predicted via RNA velocity could help create more informative low dimensional embeddings of single cell data. doi.org/10.1093/bioinf… (1/5)

I've developed a model of combination chemotherapy and trained it on DLBCL trials. The ultimate test of my model is to predict new trial results, so I predicted the results of the POLARIX trial. Today I got to check the predictions, and they were right! bit.ly/3yuf0MC

In the March Issue of Cancer Discovery, Independent Drug Action in Combination Therapy: Implications for Precision Oncology by Deborah Plana, MD, PhD, Adam C Palmer, and Peter Sorger. bit.ly/35VjKAK HMS_SysBio The Harvard/MIT MD-PhD Program Harvard Medical School HST @HiTSatHarvard

New paper: Most approved drug combinations for advanced cancer (1995-2020) have predictable clinical efficacy, because they have additive effect on Progression-Free Survival times. In Nature Cancer at rdcu.be/drhs0 by Haeun (Hannah) Hwangbo Sarah Patterson Deborah Plana, MD, PhD 1/6

Graduating physician-scientist Deborah Plana combines a passion for analysis and improving patient care hms.harvard.edu/news/seeing-hu…