🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

13 Jan 23: We had a wonderful time celebrating 10 years of the lab, how time flies! It was fantastic to see the former and current members of the team. You can only accomplish great things when surrounded by great people. A big thank you to all!

As part of our 10 years of the lab celebration, we had a lot of fun exploring our artistic side of epigenetics with the scientific illustrator Julie Gamart. Some common interest of the lab: chocolate, cycling, climbing, and animals!

We have received €80,000 from SFCE, a joint contribution from Imagine for Margo and Enfants Cancer Santé. This will allow us to validate a new therapeutic target in high-grade pediatric gliomas carrying mutations in histone H3.3. We are very grateful for their support!

👏Congrats to @JujuDabin, Margherita Mori & Sophie Polo Lab for their new review in Current Opinion in Cell Biology (Elsevier | ScienceDirect)! "The #DNA #damage response in the #chromatin context: A coordinated process"🧬 👉sciencedirect.com/science/articl…

Congratulations to Juliette @JujuDabin for being awarded a postdoc fellowship as part of the Marie Skłodowska-Curie Actions of Horizon Europe to study epigenome establishment and maintenance of the inactive X chromosome after DNA double-strand breaks in mammalian cells.

Our team is seeking for a post-doc to address the role of SWI/SNF chromatin remodelers in DNA damage response. The position is funded for 2 years through an ANR and can start from October 2023. Contact me directly. Please RT

🚨 #JobAlert 🗄️Assistant·e en #gestion administrative pour une unité mixte de recherche (@INSB_CNRS, Université Paris Cité) 📍 Paris Epigenetics, Paris 🇫🇷 🗓️ CDD 18 mois ⌛️Début du contrat : septembre 2023 + d'infos et candidatures 👉emploi.cnrs.fr/Offres/CDD/UMR…

🤩This is how we celebrated science during the Fête de la science #FDS2023! 👉epigenetics.u-paris.fr/we-celebrated-… With Mikaëlle Bocel Valerie Drouet Annalisa Verrico Margherita Mori Kamal Bouhali Angélique AMO Léo Carrillo Emmanuel Cazottes Université Paris Cité CNRS Biologie CNRS Île-de-France Villejuif

Congratulations Audrey Chansard (@audrey_945) and Sandra Piquet! 👏

👏🏻Congratulations Enrico Pobega on your remarkable PhD defense! The work entitled "Exploring the interplay between facultative #heterochromatin and #DNA double-strand break repair" was done under the supervision of Sophie Polo, Sophie Polo Lab 🧬

❗️#Chromatin dynamics and nuclear organization in #genome maintenance ❗️ 🗓️June 17–20, 2024 📍Leiden, Netherlands (Hybrid) ⏳Registration by April 1 EMBO workshop organized by Sophie Polo Lab, Haico van Attikum @haicovanattikum.bsky.social, Evi Soutoglou, Gaëlle Legube lab Chromatin Repair & Philipp Oberdoerffer meetings.embo.org/event/24-chrom…

Check out our last paper focusing on altered DNA repair in H3.3 mutant pediatric high-grade glioma! We identified a specific molecular vulnerability with potential for therapeutic targeting. Thank you to our collaborators. pubmed.ncbi.nlm.nih.gov/38214234/

Deadline approaching for the EMBO workshop "Chromatin dynamics and nuclear organisation in genome maintenance", June 17-20, 2024, Leiden, the Netherlands. Speaker slots available! Register before April 1, 2024! meetings.embo.org/event/24-chrom…….

You can still register for online attendance of the hybrid EMBO workshop "Chromatin dynamics and nuclear organisation in genome maintenance", June 17-20, 2024, Leiden, NL. Deadline for registration May 15, 2024! Great speaker line-up, check it out! meetings.embo.org/event/24-chrom…

👏Congratulations Giulia Giacomini and Margherita Mori (Margherita Mori), team Sophie Polo Lab, on obtaining 4th year PhD fellowships from the Fondation pour la Recherche Médicale and La Ligue contre le cancer ! epigenetics.u-paris.fr/4th-year-phd-f…

Check out our last review on "New facets in the chromatin-based regulation of genome maintenance" sciencedirect.com/science/articl…

Great EMBO #chromatin2024 workshop in Leiden with Sophie Polo Lab Philipp Oberdoerffer Román Gonzalez-Prieto Kyle Miller @FMattiroli Ross Chapman Felipe Cortés Ledesma altmeyerlab PfanderLab Nitika Taneja Nikolay Tsanov

We are recruiting a Post doc to work on Epigenetics and Cancer!

In our new paper, we uncover a damaged chromatin marking mechanism that drives the non-random segregation of UV damage through mitosis. Chromatin alterations impinge on genome stability by controlling DNA damage segregation See Ferrand*, Dabin* et al., Nat Commun 2025.

Friends, Our lab collectively decided to move where the sky is blue. To stay informed about our latest updates (job opportunities, publications, etc.), please follow us on our other platform. See you soon!