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The end of my PhD saga is in sight. I’m ready to face the viva and move on to the next chapter of my life. "Believe you can and you’re halfway there." – Theodore Roosevelt CCMB Sankar's Lab #acade

Pradeep kumar and Sankaranarayanan Rajan write on how Paul Berg and Donald Crother's findings that were against the understanding of those times led their work to unexpected turns of unraveling evolution of different life forms. academic.oup.com/nar/advance-ar… CSIR, India

Dive into the past with our latest review, uncovering a surprising connection between Paul Berg's and Donald Crothers' work! A blend of science and history that will leave you amazed! #historicalperspective #sciencemystery Sankaranarayanan Rajan CCMB Nucleic Acids Res academic.oup.com/nar/article/do…

This was started as a discussion with my guide Sankaranarayanan Rajan. Happy to see this in its final form, and I learned a lot while preparing it. On a lighter note, we prepared this video of Paul Berg meeting Donald Crothers in a parallel world and discussing the progress on DTD!

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📢 We're hiring! Two positions open for Project Students at our lab. If you're a hard-working and motivated student, passionate about structural biology, we want to hear from you! To know more about us check sankarslab.weebly.com For applying 👇 shorturl.at/grZ04

How to pick a problem. Today in Cell. 1/53 cell.com/cell/fulltext/…

Reducing the complexity of a fascinating molecular motor. Read our Behind the Paper blog, where we detail our journey to deciphering the structural basis for how bacterial flagella shift into reverse gear: communities.springernature.com/posts/let-slip…

Animal speed comparison

Starting the new phase of life as a postdoctoral fellow at MIT and Broad institute!

Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. MouseMapper showed obesity-induced changes in facial nerves & body-wide inflammation 👉🏼🧵biorxiv.org/content/10.110…

Excited to share that our latest work on Fanzor is now online in Cell ! By analyzing structures from different species, we’ve uncovered the structural diversity and how they cut DNA. Huge thanks to Feng Feng Zhang , Makoto, and all collaborators! cell.com/cell/fulltext/…

Nature is amazing! Congratulations to Max Wilkinson and team on a beautiful study revealing a clever way that bacteria defend against viruses. Check out Max’s posts for more detail! doi.org/10.1126/scienc…

Incredible story of bacterial defence against viral infection! Kudos to Max Wilkinson !!

Excited to see our team’s work on Fanzor now published in Cell! Amazing effort by Peiyu Xu and the entire team in uncovering the structural diversity and DNA cutting mechanisms of Fanzor. Proud of everyone involved! Onward to more discoveries. 🚀

Happy 2025=1^3+2^3+3^3+4^3+5^3+6^3+7^3+8^3+9^3 and many new discoveries!

Exciting work from Kalli Kappel - using pooled optical screening to determine sequence features that contribute to condensate formation! If interested in this topic reach out to Kalli, who just started her lab at UCLA. She is an amazingly insightful scientist and a great person!

Can we use RNA to insert kilobases of DNA into the human genome, opening up a new way to engineer cells or treat disease? Excited to share our latest work turning a retrotransposon (a “jumping gene” with an RNA intermediate) from songbirds into a genome editing tool. 🧵 (1/7)